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Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH.
Wilson AD, Richards MA, Curtis MK, Gunadasa-Rohling M, Monterisi S, Loonat AA, Miller JJ, Ball V, Lewis A, Tyler DJ, Moshnikova A, Andreev OA, Reshetnyak YK, Carr C, Swietach P. Wilson AD, et al. Among authors: lewis a. Cardiovasc Res. 2022 Nov 10;118(14):2946-2959. doi: 10.1093/cvr/cvab364. Cardiovasc Res. 2022. PMID: 34897412 Free PMC article.
Hyperpolarized [1,4-13C2]Fumarate Enables Magnetic Resonance-Based Imaging of Myocardial Necrosis.
Miller JJ, Lau AZ, Nielsen PM, McMullen-Klein G, Lewis AJ, Jespersen NR, Ball V, Gallagher FA, Carr CA, Laustsen C, Bøtker HE, Tyler DJ, Schroeder MA. Miller JJ, et al. Among authors: lewis aj. JACC Cardiovasc Imaging. 2018 Nov;11(11):1594-1606. doi: 10.1016/j.jcmg.2017.09.020. Epub 2017 Dec 13. JACC Cardiovasc Imaging. 2018. PMID: 29248653 Free PMC article.
4,340 results