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Bisphosphonates: The role of chemistry in understanding their biological actions and structure-activity relationships, and new directions for their therapeutic use.
Ebetino FH, Sun S, Cherian P, Roshandel S, Neighbors JD, Hu E, Dunford JE, Sedghizadeh PP, McKenna CE, Srinivasan V, Boeckman RK, Russell RGG. Ebetino FH, et al. Among authors: cherian p. Bone. 2022 Mar;156:116289. doi: 10.1016/j.bone.2021.116289. Epub 2021 Dec 8. Bone. 2022. PMID: 34896359 Free PMC article.
Bisphosphonates for delivering drugs to bone.
Sun S, Tao J, Sedghizadeh PP, Cherian P, Junka AF, Sodagar E, Xing L, Boeckman RK Jr, Srinivasan V, Yao Z, Boyce BF, Lipe B, Neighbors JD, Russell RGG, McKenna CE, Ebetino FH. Sun S, et al. Among authors: cherian p. Br J Pharmacol. 2021 May;178(9):2008-2025. doi: 10.1111/bph.15251. Epub 2021 Apr 10. Br J Pharmacol. 2021. PMID: 32876338 Free PMC article. Review.
Development of Bisphosphonate-Conjugated Antibiotics to Overcome Pharmacodynamic Limitations of Local Therapy: Initial Results with Carbamate Linked Sitafloxacin and Tedizolid.
Adjei-Sowah E, Peng Y, Weeks J, Jonason JH, de Mesy Bentley KL, Masters E, Morita Y, Muthukrishnan G, Cherian P, Hu XE, McKenna CE, Ebetino FH, Sun S, Schwarz EM, Xie C. Adjei-Sowah E, et al. Among authors: cherian p. Antibiotics (Basel). 2021 Jun 17;10(6):732. doi: 10.3390/antibiotics10060732. Antibiotics (Basel). 2021. PMID: 34204351 Free PMC article.
Efficacy of Bisphosphonate-Conjugated Sitafloxacin in a Murine Model of S. aureus Osteomyelitis: Evidence of "Target & Release" Kinetics and Killing of Bacteria Within Canaliculi.
Ren Y, Xue T, Rainbolt J, Bentley KLM, Galloway CA, Liu Y, Cherian P, Neighbors J, Hofstee MI, Ebetino FH, Moriarty TF, Sun S, Schwarz EM, Xie C. Ren Y, et al. Among authors: cherian p. Front Cell Infect Microbiol. 2022 Jun 24;12:910970. doi: 10.3389/fcimb.2022.910970. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35811672 Free PMC article.
Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene diphosphonate.
Okawa H, Kondo T, Hokugo A, Cherian P, Campagna JJ, Lentini NA, Sung EC, Chiang S, Lin YL, Ebetino FH, John V, Sun S, McKenna CE, Nishimura I. Okawa H, et al. Among authors: cherian p. Elife. 2022 Aug 26;11:e76207. doi: 10.7554/eLife.76207. Elife. 2022. PMID: 36017995 Free PMC article.
Real-Time Impedance-Based Monitoring of the Growth and Inhibition of Osteomyelitis Biofilm Pathogen Staphylococcus aureus Treated with Novel Bisphosphonate-Fluoroquinolone Antimicrobial Conjugates.
Sedghizadeh PP, Cherian P, Roshandel S, Tjokro N, Chen C, Junka AF, Hu E, Neighbors J, Pawlak J, Russell RGG, McKenna CE, Ebetino FH, Sun S, Sodagar E. Sedghizadeh PP, et al. Among authors: cherian p. Int J Mol Sci. 2023 Jan 19;24(3):1985. doi: 10.3390/ijms24031985. Int J Mol Sci. 2023. PMID: 36768310 Free PMC article.
229 results