Miller DJ - Search Results

1

Biophysical analysis of the Mycobacteria tuberculosis peptide binding protein DppA reveals a stringent peptide binding pocket.

Fernando DM, Gee CT, Griffith EC, Meyer CJ, Wilt LA, Tangallapally R, Wallace MJ, Miller DJ, Lee RE. Fernando DM, et al. Among authors: miller dj. Tuberculosis (Edinb). 2022 Jan;132:102157. doi: 10.1016/j.tube.2021.102157. Epub 2021 Nov 29. Tuberculosis (Edinb). 2022. PMID: 34894561 Free PMC article.

2

Mechanistic Insight on the Mode of Action of Colletoic Acid.

Ling T, Miller DJ, Lang WH, Griffith E, Rodriguez-Cortes A, El Ayachi I, Palacios G, Min J, Miranda-Carboni G, Lee RE, Rivas F. Ling T, et al. Among authors: miller dj. J Med Chem. 2019 Aug 8;62(15):6925-6940. doi: 10.1021/acs.jmedchem.9b00187. Epub 2019 Jul 24. J Med Chem. 2019. PMID: 31294974 Free PMC article.

3

Ureadepsipeptides as ClpP Activators.

Griffith EC, Zhao Y, Singh AP, Conlon BP, Tangallapally R, Shadrick WR, Liu J, Wallace MJ, Yang L, Elmore JM, Li Y, Zheng Z, Miller DJ, Cheramie MN, Lee RB, LaFleur MD, Lewis K, Lee RE. Griffith EC, et al. Among authors: miller dj. ACS Infect Dis. 2019 Nov 8;5(11):1915-1925. doi: 10.1021/acsinfecdis.9b00245. Epub 2019 Oct 24. ACS Infect Dis. 2019. PMID: 31588734 Free PMC article.

4

Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.

Yang SW, Huang X, Lin W, Min J, Miller DJ, Mayasundari A, Rodrigues P, Griffith EC, Gee CT, Li L, Li W, Lee RE, Rankovic Z, Chen T, Potts PR. Yang SW, et al. Among authors: miller dj. Nat Commun. 2020 Oct 1;11(1):4931. doi: 10.1038/s41467-020-18708-x. Nat Commun. 2020. PMID: 33004795 Free PMC article.

5

Biochemical Roles for Conserved Residues in the Bacterial Fatty Acid-binding Protein Family.

Broussard TC, Miller DJ, Jackson P, Nourse A, White SW, Rock CO. Broussard TC, et al. Among authors: miller dj. J Biol Chem. 2016 Mar 18;291(12):6292-303. doi: 10.1074/jbc.M115.706820. Epub 2016 Jan 16. J Biol Chem. 2016. PMID: 26774272 Free PMC article.

6

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.

Pan M, Wright WC, Chapple RH, Zubair A, Sandhu M, Batchelder JE, Huddle BC, Low J, Blankenship KB, Wang Y, Gordon B, Archer P, Brady SW, Natarajan S, Posgai MJ, Schuetz J, Miller D, Kalathur R, Chen S, Connelly JP, Babu MM, Dyer MA, Pruett-Miller SM, Freeman BB 3rd, Chen T, Godley LA, Blanchard SC, Stewart E, Easton J, Geeleher P. Pan M, et al. Nat Commun. 2021 Nov 9;12(1):6468. doi: 10.1038/s41467-021-26640-x. Nat Commun. 2021. PMID: 34753908 Free PMC article.

7

Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein.

Lin W, Huber AD, Poudel S, Li Y, Seetharaman J, Miller DJ, Chen T. Lin W, et al. Among authors: miller dj. Proc Natl Acad Sci U S A. 2023 Mar 7;120(10):e2217804120. doi: 10.1073/pnas.2217804120. Epub 2023 Feb 27. Proc Natl Acad Sci U S A. 2023. PMID: 36848571 Free PMC article.

8

Ligand flexibility and binding pocket malleability cooperate to allow selective PXR activation by analogs of a promiscuous nuclear receptor ligand.

Huber AD, Poudel S, Li Y, Lin W, Wu J, Miller DJ, Chen T. Huber AD, et al. Among authors: miller dj. Structure. 2023 Dec 7;31(12):1545-1555.e9. doi: 10.1016/j.str.2023.08.020. Epub 2023 Sep 19. Structure. 2023. PMID: 37729916

9

How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.

Regni CA, Roush RF, Miller DJ, Nourse A, Walsh CT, Schulman BA. Regni CA, et al. Among authors: miller dj. EMBO J. 2009 Jul 8;28(13):1953-64. doi: 10.1038/emboj.2009.146. Epub 2009 Jun 4. EMBO J. 2009. PMID: 19494832 Free PMC article.

10

The genome of a Bacteroidetes inhabitant of the human gut encodes a structurally distinct enoyl-acyl carrier protein reductase (FabI).

Radka CD, Frank MW, Yao J, Seetharaman J, Miller DJ, Rock CO. Radka CD, et al. Among authors: miller dj. J Biol Chem. 2020 May 29;295(22):7635-7652. doi: 10.1074/jbc.RA120.013336. Epub 2020 Apr 21. J Biol Chem. 2020. PMID: 32317282 Free PMC article.

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