Isoherranen N - Search Results

1

Infant Dextromethorphan and Dextrorphan Exposure via Breast Milk From Mothers Who Are CYP2D6 Extensive Metabolizers.

Shum S, Yadav A, Fay E, Moreni S, Mao J, Czuba L, Wang C, Isoherranen N, Hebert MF. Shum S, et al. Among authors: isoherranen n. J Clin Pharmacol. 2022 Jun;62(6):747-755. doi: 10.1002/jcph.2012. Epub 2022 Jan 8. J Clin Pharmacol. 2022. PMID: 34889461 Free PMC article.

2

Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro.

Dai Y, Hebert MF, Isoherranen N, Davis CL, Marsh C, Shen DD, Thummel KE. Dai Y, et al. Among authors: isoherranen n. Drug Metab Dispos. 2006 May;34(5):836-47. doi: 10.1124/dmd.105.008680. Epub 2006 Feb 24. Drug Metab Dispos. 2006. PMID: 16501005

3

Contribution of itraconazole metabolites to inhibition of CYP3A4 in vivo.

Templeton IE, Thummel KE, Kharasch ED, Kunze KL, Hoffer C, Nelson WL, Isoherranen N. Templeton IE, et al. Among authors: isoherranen n. Clin Pharmacol Ther. 2008 Jan;83(1):77-85. doi: 10.1038/sj.clpt.6100230. Epub 2007 May 9. Clin Pharmacol Ther. 2008. PMID: 17495874 Free PMC article. Clinical Trial.

4

Changes in maternal liver Cyp2c and Cyp2d expression and activity during rat pregnancy.

Dickmann LJ, Tay S, Senn TD, Zhang H, Visone A, Unadkat JD, Hebert MF, Isoherranen N. Dickmann LJ, et al. Among authors: isoherranen n. Biochem Pharmacol. 2008 Apr 15;75(8):1677-87. doi: 10.1016/j.bcp.2008.01.012. Epub 2008 Feb 7. Biochem Pharmacol. 2008. PMID: 18342837 Free PMC article.

5

Contributions of human cytochrome P450 enzymes to glyburide metabolism.

Zhou L, Naraharisetti SB, Liu L, Wang H, Lin YS, Isoherranen N, Unadkat JD, Hebert MF, Mao Q. Zhou L, et al. Among authors: isoherranen n. Biopharm Drug Dispos. 2010 May;31(4):228-42. doi: 10.1002/bdd.706. Biopharm Drug Dispos. 2010. PMID: 20437462 Free PMC article.

6

Accurate prediction of dose-dependent CYP3A4 inhibition by itraconazole and its metabolites from in vitro inhibition data.

Templeton I, Peng CC, Thummel KE, Davis C, Kunze KL, Isoherranen N. Templeton I, et al. Among authors: isoherranen n. Clin Pharmacol Ther. 2010 Oct;88(4):499-505. doi: 10.1038/clpt.2010.119. Epub 2010 Aug 25. Clin Pharmacol Ther. 2010. PMID: 20739919 Free PMC article. Clinical Trial.

7

Are circulating metabolites important in drug-drug interactions?: Quantitative analysis of risk prediction and inhibitory potency.

Yeung CK, Fujioka Y, Hachad H, Levy RH, Isoherranen N. Yeung CK, et al. Among authors: isoherranen n. Clin Pharmacol Ther. 2011 Jan;89(1):105-13. doi: 10.1038/clpt.2010.252. Epub 2010 Dec 1. Clin Pharmacol Ther. 2011. PMID: 21124313 Free PMC article.

8

Prediction of relative in vivo metabolite exposure from in vitro data using two model drugs: dextromethorphan and omeprazole.

Lutz JD, Isoherranen N. Lutz JD, et al. Among authors: isoherranen n. Drug Metab Dispos. 2012 Jan;40(1):159-68. doi: 10.1124/dmd.111.042200. Epub 2011 Oct 18. Drug Metab Dispos. 2012. PMID: 22010218 Free PMC article.

9

A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women.

Ke AB, Nallani SC, Zhao P, Rostami-Hodjegan A, Isoherranen N, Unadkat JD. Ke AB, et al. Among authors: isoherranen n. Drug Metab Dispos. 2013 Apr;41(4):801-13. doi: 10.1124/dmd.112.050161. Epub 2013 Jan 25. Drug Metab Dispos. 2013. PMID: 23355638 Free PMC article.

10

Fluoxetine- and norfluoxetine-mediated complex drug-drug interactions: in vitro to in vivo correlation of effects on CYP2D6, CYP2C19, and CYP3A4.

Sager JE, Lutz JD, Foti RS, Davis C, Kunze KL, Isoherranen N. Sager JE, et al. Among authors: isoherranen n. Clin Pharmacol Ther. 2014 Jun;95(6):653-62. doi: 10.1038/clpt.2014.50. Epub 2014 Feb 25. Clin Pharmacol Ther. 2014. PMID: 24569517 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

167 results

Search Page