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Molecular Mechanisms of Anticancer Activity of N-Glycosides of Indolocarbazoles LCS-1208 and LCS-1269.
Molecules. 2021 Dec 2;26(23):7329. doi: 10.3390/molecules26237329.
Molecules. 2021.
PMID: 34885910
Free PMC article.
[3-(1H-indol-3-yl)-4-(1-glykozylindol-3-yl)-1H-pyrrole-2,5-diones: synthesis and study of antiproliferative properties].
Mel'nik SIa, Bakhmedova AA, Garaeva LD, Miniker TD, Plikhtiak IL, Ektova LV, Ivanova TP, Adanin VM, Iartseva IV.
Mel'nik SIa, et al. Among authors: ektova lv.
Bioorg Khim. 1996 Oct-Nov;22(10-11):832-7.
Bioorg Khim. 1996.
PMID: 9036842
Russian.
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[Synthesis and antiproliferative properties of glycosides of bis(indolyl)furan-2,5-dione and bis(indolyl)-1H-pyrrol-2,5-dione].
Mel'nik SIa, Bakhmedova AA, Garaeva LD, Goriunova OV, Miniker TD, Plikhtiak IL, Ektova LV, Iartseva IV.
Mel'nik SIa, et al. Among authors: ektova lv.
Bioorg Khim. 1996 Jun;22(6):458-67.
Bioorg Khim. 1996.
PMID: 8975674
Russian.
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[Synthesis and biological properties of pyrimidine 2'-deoxynucleosides modified by a residue of quinaldic acid].
Ektova LV, Iartseva IV, Khorosheva EV, Ivanova TP, Iavorskaia NP, Mel'nik SIa.
Ektova LV, et al.
Bioorg Khim. 1995 Aug;21(8):625-31.
Bioorg Khim. 1995.
PMID: 8540903
Russian.
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[Synthesis and properties of an acyclic analog of 9-deazainosine and related compounds].
Ektova LV, Tolkachev VN, Sizova OS, Nikolaeva TG, Pilipenko TV.
Ektova LV, et al.
Bioorg Khim. 1985 Aug;11(8):1105-9.
Bioorg Khim. 1985.
PMID: 2998402
Russian.
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A novel glycosylated indolocarbazole derivative LCS1269 effectively inhibits growth of human cancer cells in vitro and in vivo through driving of both apoptosis and senescence by inducing of DNA damage and modulating of AKT/mTOR/S6K and ERK pathways.
Kalitin NN, Ektova LV, Kostritsa NS, Sivirinova AS, Kostarev AV, Smirnova GB, Borisova YA, Golubeva IS, Ermolaeva EV, Vergun MA, Babaeva MA, Lushnikova AA, Karamysheva AF.
Kalitin NN, et al. Among authors: ektova lv.
Chem Biol Interact. 2022 Sep 1;364:110056. doi: 10.1016/j.cbi.2022.110056. Epub 2022 Jul 21.
Chem Biol Interact. 2022.
PMID: 35872044
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