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Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
Golebiewska A, Hau AC, Oudin A, Stieber D, Yabo YA, Baus V, Barthelemy V, Klein E, Bougnaud S, Keunen O, Wantz M, Michelucci A, Neirinckx V, Muller A, Kaoma T, Nazarov PV, Azuaje F, De Falco A, Flies B, Richart L, Poovathingal S, Arns T, Grzyb K, Mock A, Herold-Mende C, Steino A, Brown D, May P, Miletic H, Malta TM, Noushmehr H, Kwon YJ, Jahn W, Klink B, Tanner G, Stead LF, Mittelbronn M, Skupin A, Hertel F, Bjerkvig R, Niclou SP. Golebiewska A, et al. Among authors: mittelbronn m. Acta Neuropathol. 2020 Dec;140(6):919-949. doi: 10.1007/s00401-020-02226-7. Epub 2020 Oct 3. Acta Neuropathol. 2020. PMID: 33009951 Free PMC article.
Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration.
Ilina EI, Cialini C, Gerloff DL, Duarte Garcia-Escudero M, Jeanty C, Thézénas ML, Lesur A, Puard V, Bernardin F, Moter A, Schuster A, Dieterle M, Golebiewska A, Gérardy JJ, Dittmar G, Niclou SP, Müller T, Mittelbronn M. Ilina EI, et al. Among authors: mittelbronn m. iScience. 2022 Feb 2;25(2):103842. doi: 10.1016/j.isci.2022.103842. eCollection 2022 Feb 18. iScience. 2022. PMID: 35198895 Free PMC article.
Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies.
Fixemer S, Ameli C, Hammer G, Salamanca L, Uriarte Huarte O, Schwartz C, Gérardy JJ, Mechawar N, Skupin A, Mittelbronn M, Bouvier DS. Fixemer S, et al. Among authors: mittelbronn m. Acta Neuropathol Commun. 2022 Mar 16;10(1):36. doi: 10.1186/s40478-022-01342-7. Acta Neuropathol Commun. 2022. PMID: 35296366 Free PMC article.
Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells.
Franchina DG, Kurniawan H, Grusdat M, Binsfeld C, Guerra L, Bonetti L, Soriano-Baguet L, Ewen A, Kobayashi T, Farinelle S, Minafra AR, Vandamme N, Carpentier A, Borgmann FK, Jäger C, Chen Y, Kleinewietfeld M, Vasiliou V, Mittelbronn M, Hiller K, Lang PA, Brenner D. Franchina DG, et al. Among authors: mittelbronn m. Nat Commun. 2022 Apr 4;13(1):1789. doi: 10.1038/s41467-022-29426-x. Nat Commun. 2022. PMID: 35379825 Free PMC article.
Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation.
Wasner K, Smajic S, Ghelfi J, Delcambre S, Prada-Medina CA, Knappe E, Arena G, Mulica P, Agyeah G, Rakovic A, Boussaad I, Badanjak K, Ohnmacht J, Gérardy JJ, Takanashi M, Trinh J, Mittelbronn M, Hattori N, Klein C, Antony P, Seibler P, Spielmann M, Pereira SL, Grünewald A. Wasner K, et al. Among authors: mittelbronn m. Mov Disord. 2022 Jul;37(7):1405-1415. doi: 10.1002/mds.29025. Epub 2022 Apr 23. Mov Disord. 2022. PMID: 35460111
337 results