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Structure of a Potential Therapeutic Antibody Bound to Interleukin-16 (IL-16): MECHANISTIC INSIGHTS AND NEW THERAPEUTIC OPPORTUNITIES.
Hall G, Cullen E, Sawmynaden K, Arnold J, Fox S, Cowan R, Muskett FW, Matthews D, Merritt A, Kettleborough C, Cruikshank W, Taylor D, Bayliss R, Carr MD. Hall G, et al. Among authors: matthews d. J Biol Chem. 2016 Aug 5;291(32):16840-8. doi: 10.1074/jbc.M115.709303. Epub 2016 May 26. J Biol Chem. 2016. PMID: 27231345 Free PMC article.
Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses.
Bullen G, Galson JD, Hall G, Villar P, Moreels L, Ledsgaard L, Mattiuzzo G, Bentley EM, Masters EW, Tang D, Millett S, Tongue D, Brown R, Diamantopoulos I, Parthiban K, Tebbutt C, Leah R, Chaitanya K, Ergueta-Carballo S, Pazeraitis D, Surade SB, Ashiru O, Crippa L, Cowan R, Bowler MW, Campbell JI, Lee WJ, Carr MD, Matthews D, Pfeffer P, Hufton SE, Sawmynaden K, Osbourn J, McCafferty J, Karatt-Vellatt A. Bullen G, et al. Among authors: matthews d. Front Immunol. 2021 Jun 15;12:678570. doi: 10.3389/fimmu.2021.678570. eCollection 2021. Front Immunol. 2021. PMID: 34211469 Free PMC article.
An antagonistic monoclonal anti-Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis.
Vogler M, Oleksy A, Schulze S, Fedorova M, Kojonazarov B, Nijjar S, Patel S, Jossi S, Sawmynaden K, Henry M, Brown R, Matthews D, Offermanns S, Worzfeld T. Vogler M, et al. Among authors: matthews d. J Biol Chem. 2022 Sep;298(9):102265. doi: 10.1016/j.jbc.2022.102265. Epub 2022 Jul 15. J Biol Chem. 2022. PMID: 35850304 Free PMC article.
Mechanochemical control of epidermal stem cell divisions by B-plexins.
Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernández-Baldovinos J, Zhou L, Höß C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Gröne HJ, Graumann PL, Niessen CM, Offermanns S, Wickström SA, Worzfeld T. Jiang C, et al. Among authors: matthews d. Nat Commun. 2021 Feb 26;12(1):1308. doi: 10.1038/s41467-021-21513-9. Nat Commun. 2021. PMID: 33637728 Free PMC article.
The effect of TG2-inhibitory monoclonal antibody zampilimab on tissue fibrosis in human in vitro and primate in vivo models of chronic kidney disease.
Huang L, Bon H, Maamra M, Holmes T, Atkinson J, Cain K, Kennedy J, Kettleborough C, Matthews D, Twomey B, Ni J, Song Z, Watson PF, Johnson TS. Huang L, et al. Among authors: matthews d. PLoS One. 2024 May 16;19(5):e0298864. doi: 10.1371/journal.pone.0298864. eCollection 2024. PLoS One. 2024. PMID: 38753630 Free PMC article.
2,027 results