Evans GB - Search Results

1

Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer.

Luxenburger A, Bougen-Zhukov N, Fraser MG, Beetham H, Harris LD, Schmidt D, Cameron SA, Guilford PJ, Evans GB. Luxenburger A, et al. Among authors: evans gb. J Med Chem. 2021 Dec 23;64(24):18114-18142. doi: 10.1021/acs.jmedchem.1c01609. Epub 2021 Dec 8. J Med Chem. 2021. PMID: 34878770

2

The synthesis and antibacterial activity of totarol derivatives. Part 1: modifications of ring-C and pro-drugs.

Evans GB, Furneaux RH, Gravestock MB, Lynch GP, Scott GK. Evans GB, et al. Bioorg Med Chem. 1999 Sep;7(9):1953-64. doi: 10.1016/s0968-0896(99)00162-5. Bioorg Med Chem. 1999. PMID: 10530944

3

Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases.

Zhang Y, Evans GB, Clinch K, Crump DR, Harris LD, Fröhlich RF, Tyler PC, Hazleton KZ, Cassera MB, Schramm VL. Zhang Y, et al. Among authors: evans gb. J Biol Chem. 2013 Nov 29;288(48):34746-54. doi: 10.1074/jbc.M113.521955. Epub 2013 Oct 24. J Biol Chem. 2013. PMID: 24158442 Free PMC article.

4

Tight binding enantiomers of pre-clinical drug candidates.

Evans GB, Cameron SA, Luxenburger A, Guan R, Suarez J, Thomas K, Schramm VL, Tyler PC. Evans GB, et al. Bioorg Med Chem. 2015 Sep 1;23(17):5326-33. doi: 10.1016/j.bmc.2015.07.059. Epub 2015 Jul 30. Bioorg Med Chem. 2015. PMID: 26260335 Free PMC article.

5

New Antibiotic Candidates against Helicobacter pylori.

Wang S, Cameron SA, Clinch K, Evans GB, Wu Z, Schramm VL, Tyler PC. Wang S, et al. Among authors: evans gb. J Am Chem Soc. 2015 Nov 18;137(45):14275-80. doi: 10.1021/jacs.5b06110. Epub 2015 Nov 9. J Am Chem Soc. 2015. PMID: 26494017 Free PMC article.

6

Oligonucleotide transition state analogues of saporin L3.

Mason JM, Yuan H, Evans GB, Tyler PC, Du Q, Schramm VL. Mason JM, et al. Among authors: evans gb. Eur J Med Chem. 2017 Feb 15;127:793-809. doi: 10.1016/j.ejmech.2016.10.059. Epub 2016 Oct 27. Eur J Med Chem. 2017. PMID: 27823883 Free PMC article.

7

A Designed Approach to Enantiodivergent Enamine Catalysis.

Macharia J, Wambua V, Hong Y, Harris L, Hirschi JS, Evans GB, Vetticatt MJ. Macharia J, et al. Among authors: evans gb. Angew Chem Int Ed Engl. 2017 Jul 17;56(30):8756-8760. doi: 10.1002/anie.201703919. Epub 2017 Jun 20. Angew Chem Int Ed Engl. 2017. PMID: 28544165

8

Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase.

Harris LD, Harijan RK, Ducati RG, Evans GB, Hirsch BM, Schramm VL. Harris LD, et al. Among authors: evans gb. ACS Chem Biol. 2018 Jan 19;13(1):152-160. doi: 10.1021/acschembio.7b00601. Epub 2017 Dec 14. ACS Chem Biol. 2018. PMID: 29178779 Free PMC article.

9

E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.

Godwin TD, Kelly ST, Brew TP, Bougen-Zhukov NM, Single AB, Chen A, Stylianou CE, Harris LD, Currie SK, Telford BJ, Beetham HG, Evans GB, Black MA, Guilford PJ. Godwin TD, et al. Among authors: evans gb. Gastric Cancer. 2019 Mar;22(2):273-286. doi: 10.1007/s10120-018-0859-1. Epub 2018 Jul 31. Gastric Cancer. 2019. PMID: 30066183 Free PMC article.

10

Transition-State Analogues of Campylobacter jejuni 5'-Methylthioadenosine Nucleosidase.

Ducati RG, Harijan RK, Cameron SA, Tyler PC, Evans GB, Schramm VL. Ducati RG, et al. Among authors: evans gb. ACS Chem Biol. 2018 Nov 16;13(11):3173-3183. doi: 10.1021/acschembio.8b00781. Epub 2018 Oct 19. ACS Chem Biol. 2018. PMID: 30339406 Free PMC article.

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