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The dark side of RNA:DNA hybrids.
Brambati A, Zardoni L, Nardini E, Pellicioli A, Liberi G. Brambati A, et al. Mutat Res Rev Mutat Res. 2020 Apr-Jun;784:108300. doi: 10.1016/j.mrrev.2020.108300. Epub 2020 Feb 29. Mutat Res Rev Mutat Res. 2020. PMID: 32430097 Review.
Polθ reverse transcribes RNA and promotes RNA-templated DNA repair.
Chandramouly G, Zhao J, McDevitt S, Rusanov T, Hoang T, Borisonnik N, Treddinick T, Lopezcolorado FW, Kent T, Siddique LA, Mallon J, Huhn J, Shoda Z, Kashkina E, Brambati A, Stark JM, Chen XS, Pomerantz RT. Chandramouly G, et al. Among authors: brambati a. Sci Adv. 2021 Jun 11;7(24):eabf1771. doi: 10.1126/sciadv.abf1771. Print 2021 Jun. Sci Adv. 2021. PMID: 34117057 Free PMC article.
RHINO directs MMEJ to repair DNA breaks in mitosis.
Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A. Brambati A, et al. Science. 2023 Aug 11;381(6658):653-660. doi: 10.1126/science.adh3694. Epub 2023 Jul 13. Science. 2023. PMID: 37440612 Free PMC article.
RHINO restricts MMEJ activity to mitosis.
Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A. Brambati A, et al. bioRxiv [Preprint]. 2023 Mar 16:2023.03.16.532763. doi: 10.1101/2023.03.16.532763. bioRxiv. 2023. PMID: 36993461 Free PMC article. Updated. Preprint.
12 results