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RSK1 SUMOylation is required for KSHV lytic replication.
Liu Z, Liu C, Wang X, Li W, Zhou J, Dong P, Xiao MZX, Wang C, Zhang Y, Fu J, Zhu F, Liang Q. Liu Z, et al. Among authors: zhu f. PLoS Pathog. 2021 Dec 6;17(12):e1010123. doi: 10.1371/journal.ppat.1010123. eCollection 2021 Dec. PLoS Pathog. 2021. PMID: 34871326 Free PMC article.
Mechanisms of autoinhibition of IRF-7 and a probable model for inactivation of IRF-7 by Kaposi's sarcoma-associated herpesvirus protein ORF45.
Sathish N, Zhu FX, Golub EE, Liang Q, Yuan Y. Sathish N, et al. J Biol Chem. 2011 Jan 7;286(1):746-56. doi: 10.1074/jbc.M110.150920. Epub 2010 Oct 27. J Biol Chem. 2011. PMID: 20980251 Free PMC article.
We previously demonstrated that ORF45, a KSHV immediate-early protein as well as a tegument protein of virions, interacts with IRF-7 and inhibits virus-mediated type I interferon induction by blocking IRF-7 phosphorylation and nuclear translocation (Zhu, F. X., King …
We previously demonstrated that ORF45, a KSHV immediate-early protein as well as a tegument protein of virions, interacts with IRF-7 and inh …
Phosphorylation of eukaryotic translation initiation factor 4B (EIF4B) by open reading frame 45/p90 ribosomal S6 kinase (ORF45/RSK) signaling axis facilitates protein translation during Kaposi sarcoma-associated herpesvirus (KSHV) lytic replication.
Kuang E, Fu B, Liang Q, Myoung J, Zhu F. Kuang E, et al. Among authors: zhu f. J Biol Chem. 2011 Dec 2;286(48):41171-41182. doi: 10.1074/jbc.M111.280982. Epub 2011 Oct 12. J Biol Chem. 2011. PMID: 21994950 Free PMC article.
Activation of p90 ribosomal S6 kinases by ORF45 of Kaposi's sarcoma-associated herpesvirus is critical for optimal production of infectious viruses.
Fu B, Kuang E, Li W, Avey D, Li X, Turpin Z, Valdes A, Brulois K, Myoung J, Zhu F. Fu B, et al. Among authors: zhu f. J Virol. 2015 Jan;89(1):195-207. doi: 10.1128/JVI.01937-14. Epub 2014 Oct 15. J Virol. 2015. PMID: 25320298 Free PMC article.
We have previously shown that ORF45, an immediate-early and tegument protein of Kaposi's sarcoma-associated herpesvirus (KSHV), causes sustained activation of p90 ribosomal S6 kinases (RSKs) and extracellular regulated kinase (ERK) (E. Kuang, Q. Tang, G. G. Maul, and F. …
We have previously shown that ORF45, an immediate-early and tegument protein of Kaposi's sarcoma-associated herpesvirus (KSHV), causes susta …
7,625 results