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Immunopeptidomics-Guided Warehouse Design for Peptide-Based Immunotherapy in Chronic Lymphocytic Leukemia.
Nelde A, Maringer Y, Bilich T, Salih HR, Roerden M, Heitmann JS, Marcu A, Bauer J, Neidert MC, Denzlinger C, Illerhaus G, Aulitzky WE, Rammensee HG, Walz JS. Nelde A, et al. Among authors: marcu a. Front Immunol. 2021 Jul 8;12:705974. doi: 10.3389/fimmu.2021.705974. eCollection 2021. Front Immunol. 2021. PMID: 34305947 Free PMC article. Clinical Trial.
Autoreactive napsin A-specific T cells are enriched in lung tumors and inflammatory lung lesions during immune checkpoint blockade.
Berner F, Bomze D, Lichtensteiger C, Walter V, Niederer R, Hasan Ali O, Wyss N, Bauer J, Freudenmann LK, Marcu A, Wolfschmitt EM, Haen S, Gross T, Abdou MT, Diem S, Knöpfli S, Sinnberg T, Hofmeister K, Cheng HW, Toma M, Klümper N, Purde MT, Pop OT, Jochum AK, Pascolo S, Joerger M, Früh M, Jochum W, Rammensee HG, Läubli H, Hölzel M, Neefjes J, Walz J, Flatz L. Berner F, et al. Among authors: marcu a. Sci Immunol. 2022 Sep 2;7(75):eabn9644. doi: 10.1126/sciimmunol.abn9644. Epub 2022 Sep 2. Sci Immunol. 2022. PMID: 36054337
Identification of HCMV-derived T cell epitopes in seropositive individuals through viral deletion models.
Lübke M, Spalt S, Kowalewski DJ, Zimmermann C, Bauersfeld L, Nelde A, Bichmann L, Marcu A, Peper JK, Kohlbacher O, Walz JS, Le-Trilling VTK, Hengel H, Rammensee HG, Stevanović S, Halenius A. Lübke M, et al. Among authors: marcu a. J Exp Med. 2020 Mar 2;217(3):jem.20191164. doi: 10.1084/jem.20191164. J Exp Med. 2020. PMID: 31869419 Free PMC article.
Prostaglandin E2 in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8+ T cells.
Gierlich P, Lex V, Technau A, Keupp A, Morper L, Glunz A, Sennholz H, Rachor J, Sauer S, Marcu A, Grigoleit GU, Wölfl M, Schlegel PG, Eyrich M. Gierlich P, et al. Among authors: marcu a. Cancer Immunol Immunother. 2020 Jun;69(6):1029-1042. doi: 10.1007/s00262-019-02470-1. Epub 2020 Feb 25. Cancer Immunol Immunother. 2020. PMID: 32100075 Free PMC article.
Keratinocyte differentiation antigen-specific T cells in immune checkpoint inhibitor-treated NSCLC patients are associated with improved survival.
Berner F, Niederer R, Luimstra JJ, Pop OT, Jochum AK, Purde MT, Hasan Ali O, Bomze D, Bauer J, Freudenmann LK, Marcu A, Wolfschmitt EM, Haen S, Gross T, Dubbelaar ML, Abdou MT, Baumgaertner P, Appenzeller C, Cicin-Sain C, Lenz T, Speiser DE, Ludewig B, Driessen C, Jörger M, Früh M, Jochum W, Cozzio A, Rammensee HG, Walz J, Neefjes J, Flatz L. Berner F, et al. Among authors: marcu a. Oncoimmunology. 2021 Nov 27;10(1):2006893. doi: 10.1080/2162402X.2021.2006893. eCollection 2021. Oncoimmunology. 2021. PMID: 34858733 Free PMC article.
HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy.
Marcu A, Bichmann L, Kuchenbecker L, Kowalewski DJ, Freudenmann LK, Backert L, Mühlenbruch L, Szolek A, Lübke M, Wagner P, Engler T, Matovina S, Wang J, Hauri-Hohl M, Martin R, Kapolou K, Walz JS, Velz J, Moch H, Regli L, Silginer M, Weller M, Löffler MW, Erhard F, Schlosser A, Kohlbacher O, Stevanović S, Rammensee HG, Neidert MC. Marcu A, et al. J Immunother Cancer. 2021 Apr;9(4):e002071. doi: 10.1136/jitc-2020-002071. J Immunother Cancer. 2021. PMID: 33858848 Free PMC article.
142 results