Curtis MJ - Search Results

1

OCT2013, an ischaemia-activated antiarrhythmic prodrug, devoid of the systemic side effects of lidocaine.

Hesketh LM, Sikkel MB, Mahoney-Sanchez L, Mazzacuva F, Chowdhury RA, Tzortzis KN, Firth J, Winter J, MacLeod KT, Ogrodzinski S, Wilder CDE, Patterson LH, Peters NS, Curtis MJ. Hesketh LM, et al. Among authors: curtis mj. Br J Pharmacol. 2022 May;179(9):2037-2053. doi: 10.1111/bph.15764. Epub 2022 Jan 13. Br J Pharmacol. 2022. PMID: 34855992 Free article.

2

Contractile function assessment by intraventricular balloon alters the ability of regional ischaemia to evoke ventricular fibrillation.

Wilder CD, Masoud R, Yazar D, O'Brien BA, Eykyn TR, Curtis MJ. Wilder CD, et al. Among authors: curtis mj. Br J Pharmacol. 2016 Jan;173(1):39-52. doi: 10.1111/bph.13332. Epub 2015 Dec 4. Br J Pharmacol. 2016. PMID: 26377788 Free PMC article.

3

Facilitation of ischaemia-induced ventricular fibrillation by catecholamines is mediated by β₁ and β₂ agonism in the rat heart in vitro.

Wilder CDE, Pavlaki N, Dursun T, Gyimah P, Caldwell-Dunn E, Ranieri A, Lewis HR, Curtis MJ. Wilder CDE, et al. Among authors: curtis mj. Br J Pharmacol. 2018 May;175(10):1669-1690. doi: 10.1111/bph.14176. Epub 2018 Apr 2. Br J Pharmacol. 2018. PMID: 29473948 Free PMC article.

4

Characterisation of mexiletine's translational therapeutic index for suppression of ischaemia-induced ventricular fibrillation in the rat isolated heart.

Hesketh LM, Wilder CDE, Ranadive NN, Lytra G, Qazimi P, Munro JS, Ahdi N, Curtis MJ. Hesketh LM, et al. Among authors: curtis mj. Sci Rep. 2020 May 21;10(1):8397. doi: 10.1038/s41598-020-65190-y. Sci Rep. 2020. PMID: 32439959 Free PMC article.

5

Feasibility of targeting ischaemia-related ventricular arrhythmias by mimicry of endogenous protection by endocannabinoids.

Andrag E, Curtis MJ. Andrag E, et al. Among authors: curtis mj. Br J Pharmacol. 2013 Aug;169(8):1840-8. doi: 10.1111/bph.12252. Br J Pharmacol. 2013. PMID: 23713981 Free PMC article.

6

Selective IK blockade as an antiarrhythmic mechanism: effects of UK66,914 on ischaemia and reperfusion arrhythmias in rat and rabbit hearts.

Rees SA, Curtis MJ. Rees SA, et al. Among authors: curtis mj. Br J Pharmacol. 1993 Jan;108(1):139-45. doi: 10.1111/j.1476-5381.1993.tb13453.x. Br J Pharmacol. 1993. PMID: 8428204 Free PMC article.

7

Inadequate ischaemia-selectivity limits the antiarrhythmic efficacy of mibefradil during regional ischaemia and reperfusion in the rat isolated perfused heart.

Farkas A, Qureshi A, Curtis MJ. Farkas A, et al. Among authors: curtis mj. Br J Pharmacol. 1999 Sep;128(1):41-50. doi: 10.1038/sj.bjp.0702778. Br J Pharmacol. 1999. PMID: 10498833 Free PMC article.

8

Phase 2 ventricular arrhythmias in acute myocardial infarction: a neglected target for therapeutic antiarrhythmic drug development and for safety pharmacology evaluation.

Clements-Jewery H, Hearse DJ, Curtis MJ. Clements-Jewery H, et al. Among authors: curtis mj. Br J Pharmacol. 2005 Jul;145(5):551-64. doi: 10.1038/sj.bjp.0706231. Br J Pharmacol. 2005. PMID: 15852034 Free PMC article. Review.

9

The isolated blood-perfused rat heart: an inappropriate model for the study of ischaemia- and infarction-related ventricular fibrillation.

Clements-Jewery H, Hearse DJ, Curtis MJ. Clements-Jewery H, et al. Among authors: curtis mj. Br J Pharmacol. 2002 Dec;137(7):1089-99. doi: 10.1038/sj.bjp.0704977. Br J Pharmacol. 2002. PMID: 12429582 Free PMC article.

10

Left regional cardiac perfusion in vitro with platelet-activating factor, norepinephrine and K+ reveals that ischaemic arrhythmias are caused by independent effects of endogenous "mediators" facilitated by interactions, and moderated by paradoxical antagonism.

Baker KE, Curtis MJ. Baker KE, et al. Among authors: curtis mj. Br J Pharmacol. 2004 May;142(2):352-66. doi: 10.1038/sj.bjp.0705767. Epub 2004 Apr 5. Br J Pharmacol. 2004. PMID: 15066909 Free PMC article.

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