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Niclosamide shows strong antiviral activity in a human airway model of SARS-CoV-2 infection and a conserved potency against the Alpha (B.1.1.7), Beta (B.1.351) and Delta variant (B.1.617.2).
Weiss A, Touret F, Baronti C, Gilles M, Hoen B, Nougairède A, de Lamballerie X, Sommer MOA. Weiss A, et al. Among authors: sommer moa. PLoS One. 2021 Dec 2;16(12):e0260958. doi: 10.1371/journal.pone.0260958. eCollection 2021. PLoS One. 2021. PMID: 34855904 Free PMC article.
Niclosamide-A promising treatment for COVID-19.
Singh S, Weiss A, Goodman J, Fisk M, Kulkarni S, Lu I, Gray J, Smith R, Sommer M, Cheriyan J. Singh S, et al. Br J Pharmacol. 2022 Jul;179(13):3250-3267. doi: 10.1111/bph.15843. Epub 2022 Apr 11. Br J Pharmacol. 2022. PMID: 35348204 Free PMC article. Review.
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial.
Weiss A, Delavenne E, Matias C, Lagler H, Simon D, Li P, Hansen JU, Dos Santos TP, Jana B, Priemel P, Bangert C, Bauer M, Eberl S, Nussbaumer-Pröll A, Anne Österreicher Z, Matzneller P, Quint T, Weber M, Nielsen HM, Rades T, Johansen HK, Westh H, Kim W, Mylonakis E, Friis C, Guardabassi L, Pace J, Lundberg CV, M'Zali F, Butty P, Sørensen N, Nielsen HB, Toft-Kehler R, Guttman-Yassky E, Stingl G, Zeitlinger M, Sommer M. Weiss A, et al. Clin Transl Med. 2022 May;12(5):e790. doi: 10.1002/ctm2.790. Clin Transl Med. 2022. PMID: 35522900 Free PMC article. Clinical Trial.
Pharmacology of orismilast, a potent and selective PDE4 inhibitor.
Silverberg JI, French LE, Warren RB, Strober B, Kjøller K, Sommer MOA, Andres P, Felding J, Weiss A, Tutkunkardas D, Skak-Nielsen T, Guttman E. Silverberg JI, et al. Among authors: sommer moa. J Eur Acad Dermatol Venereol. 2023 Apr;37(4):721-729. doi: 10.1111/jdv.18818. Epub 2023 Jan 18. J Eur Acad Dermatol Venereol. 2023. PMID: 36527389
Escherichia coli Promoters with Consistent Expression throughout the Murine Gut.
Armetta J, Schantz-Klausen M, Shepelin D, Vazquez-Uribe R, Bahl MI, Laursen MF, Licht TR, Sommer MOA. Armetta J, et al. Among authors: sommer moa. ACS Synth Biol. 2021 Dec 17;10(12):3359-3368. doi: 10.1021/acssynbio.1c00325. Epub 2021 Nov 29. ACS Synth Biol. 2021. PMID: 34842418 Free article.
144 results