Swietach P - Search Results

1

What do cellular responses to acidity tell us about cancer?

Blaszczak W, Swietach P. Blaszczak W, et al. Among authors: swietach p. Cancer Metastasis Rev. 2021 Dec;40(4):1159-1176. doi: 10.1007/s10555-021-10005-3. Epub 2021 Nov 30. Cancer Metastasis Rev. 2021. PMID: 34850320 Free PMC article. Review.

2

Impaired O2 unloading from stored blood results in diffusion-limited O2 release at tissues: evidence from human kidneys.

Dumbill R, Rabcuka J, Fallon J, Knight S, Hunter J, Voyce D, Barrett J, Ellen M, Weissenbacher A, Kurniawan T, Blonski S, Korczyk PM, Ploeg R, Coussios C, Friend P, Swietach P. Dumbill R, et al. Among authors: swietach p. Blood. 2024 Feb 22;143(8):721-733. doi: 10.1182/blood.2023022385. Blood. 2024. PMID: 38048591 Free PMC article.

3

What is pH regulation, and why do cancer cells need it?

Swietach P. Swietach P. Cancer Metastasis Rev. 2019 Jun;38(1-2):5-15. doi: 10.1007/s10555-018-09778-x. Cancer Metastasis Rev. 2019. PMID: 30707328 Free PMC article. Review.

4

CRISPR-Cas9 screen identifies oxidative phosphorylation as essential for cancer cell survival at low extracellular pH.

Michl J, Wang Y, Monterisi S, Blaszczak W, Beveridge R, Bridges EM, Koth J, Bodmer WF, Swietach P. Michl J, et al. Among authors: swietach p. Cell Rep. 2022 Mar 8;38(10):110493. doi: 10.1016/j.celrep.2022.110493. Cell Rep. 2022. PMID: 35263578 Free PMC article.

5

Autoregulation of H⁺/lactate efflux prevents monocarboxylate transport (MCT) inhibitors from reducing glycolytic lactic acid production.

Blaszczak W, Williams H, Swietach P. Blaszczak W, et al. Among authors: swietach p. Br J Cancer. 2022 Oct;127(7):1365-1377. doi: 10.1038/s41416-022-01910-7. Epub 2022 Jul 15. Br J Cancer. 2022. PMID: 35840734 Free PMC article.

6

Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2.

Michl J, Monterisi S, White B, Blaszczak W, Hulikova A, Abdullayeva G, Bridges E, Yin Z, Bodmer WF, Swietach P. Michl J, et al. Among authors: swietach p. Cell Rep. 2023 Jun 27;42(6):112601. doi: 10.1016/j.celrep.2023.112601. Epub 2023 Jun 3. Cell Rep. 2023. PMID: 37270778 Free article.

7

Regulation of tumor pH and the role of carbonic anhydrase 9.

Swietach P, Vaughan-Jones RD, Harris AL. Swietach P, et al. Cancer Metastasis Rev. 2007 Jun;26(2):299-310. doi: 10.1007/s10555-007-9064-0. Cancer Metastasis Rev. 2007. PMID: 17415526 Review.

8

The chemistry, physiology and pathology of pH in cancer.

Swietach P, Vaughan-Jones RD, Harris AL, Hulikova A. Swietach P, et al. Philos Trans R Soc Lond B Biol Sci. 2014 Feb 3;369(1638):20130099. doi: 10.1098/rstb.2013.0099. Print 2014 Mar 19. Philos Trans R Soc Lond B Biol Sci. 2014. PMID: 24493747 Free PMC article. Review.

9

Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo.

Lee SH, McIntyre D, Honess D, Hulikova A, Pacheco-Torres J, Cerdán S, Swietach P, Harris AL, Griffiths JR. Lee SH, et al. Among authors: swietach p. Br J Cancer. 2018 Aug;119(5):622-630. doi: 10.1038/s41416-018-0216-5. Epub 2018 Sep 12. Br J Cancer. 2018. PMID: 30206370 Free PMC article.

10

How protons pave the way to aggressive cancers.

Swietach P, Boedtkjer E, Pedersen SF. Swietach P, et al. Nat Rev Cancer. 2023 Dec;23(12):825-841. doi: 10.1038/s41568-023-00628-9. Epub 2023 Oct 26. Nat Rev Cancer. 2023. PMID: 37884609 Review.

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