Nagalingam G - Search Results

1

Synthetic Sansanmycin Analogues as Potent Mycobacterium tuberculosis Translocase I Inhibitors.

Tran W, Kusay AS, Hawkins PME, Cheung CY, Nagalingam G, Pujari V, Ford DJ, Stoye A, Ochoa JL, Audette RE, Hortle E, Oehlers SH, Charman SA, Linington RG, Rubin EJ, Dowson CG, Roper DI, Crick DC, Balle T, Cook GM, Britton WJ, Payne RJ. Tran W, et al. Among authors: nagalingam g. J Med Chem. 2021 Dec 9;64(23):17326-17345. doi: 10.1021/acs.jmedchem.1c01407. Epub 2021 Nov 30. J Med Chem. 2021. PMID: 34845906

2

M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.

Blumenthal A, Nagalingam G, Huch JH, Walker L, Guillemin GJ, Smythe GA, Ehrt S, Britton WJ, Saunders BM. Blumenthal A, et al. Among authors: nagalingam g. PLoS One. 2012;7(5):e37314. doi: 10.1371/journal.pone.0037314. Epub 2012 May 23. PLoS One. 2012. PMID: 22649518 Free PMC article.

3

Microparticles from mycobacteria-infected macrophages promote inflammation and cellular migration.

Walters SB, Kieckbusch J, Nagalingam G, Swain A, Latham SL, Grau GE, Britton WJ, Combes V, Saunders BM. Walters SB, et al. Among authors: nagalingam g. J Immunol. 2013 Jan 15;190(2):669-77. doi: 10.4049/jimmunol.1201856. Epub 2012 Dec 14. J Immunol. 2013. PMID: 23241892

4

Total Synthesis of Teixobactin.

Giltrap AM, Dowman LJ, Nagalingam G, Ochoa JL, Linington RG, Britton WJ, Payne RJ. Giltrap AM, et al. Among authors: nagalingam g. Org Lett. 2016 Jun 3;18(11):2788-91. doi: 10.1021/acs.orglett.6b01324. Epub 2016 May 18. Org Lett. 2016. PMID: 27191730

5

Nontoxic Metal-Cyclam Complexes, a New Class of Compounds with Potency against Drug-Resistant Mycobacterium tuberculosis.

Yu M, Nagalingam G, Ellis S, Martinez E, Sintchenko V, Spain M, Rutledge PJ, Todd MH, Triccas JA. Yu M, et al. Among authors: nagalingam g. J Med Chem. 2016 Jun 23;59(12):5917-21. doi: 10.1021/acs.jmedchem.6b00432. Epub 2016 Jun 7. J Med Chem. 2016. PMID: 27214150

6

Inhalation of Respirable Crystalline Rifapentine Particles Induces Pulmonary Inflammation.

Parumasivam T, Ashhurst AS, Nagalingam G, Britton WJ, Chan HK. Parumasivam T, et al. Among authors: nagalingam g. Mol Pharm. 2017 Jan 3;14(1):328-335. doi: 10.1021/acs.molpharmaceut.6b00905. Epub 2016 Dec 15. Mol Pharm. 2017. PMID: 27977216

7

New tuberculosis drug leads from naturally occurring compounds.

Quan D, Nagalingam G, Payne R, Triccas JA. Quan D, et al. Among authors: nagalingam g. Int J Infect Dis. 2017 Mar;56:212-220. doi: 10.1016/j.ijid.2016.12.024. Epub 2017 Jan 3. Int J Infect Dis. 2017. PMID: 28062229 Free article. Review.

8

Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation.

Nagalingam G, Vinuesa CG, Britton WJ, Saunders BM. Nagalingam G, et al. J Immunol. 2017 Sep 1;199(5):1796-1804. doi: 10.4049/jimmunol.1602069. Epub 2017 Jul 26. J Immunol. 2017. PMID: 28747346 Free PMC article.

9

Delta inulin-based adjuvants promote the generation of polyfunctional CD4⁺ T cell responses and protection against Mycobacterium tuberculosis infection.

Counoupas C, Pinto R, Nagalingam G, Britton WJ, Petrovsky N, Triccas JA. Counoupas C, et al. Among authors: nagalingam g. Sci Rep. 2017 Aug 17;7(1):8582. doi: 10.1038/s41598-017-09119-y. Sci Rep. 2017. PMID: 28819247 Free PMC article.

10

Mycobacterium tuberculosis components expressed during chronic infection of the lung contribute to long-term control of pulmonary tuberculosis in mice.

Counoupas C, Pinto R, Nagalingam G, Hill-Cawthorne GA, Feng CG, Britton WJ, Triccas JA. Counoupas C, et al. Among authors: nagalingam g. NPJ Vaccines. 2016 Sep 15;1:16012. doi: 10.1038/npjvaccines.2016.12. eCollection 2016. NPJ Vaccines. 2016. PMID: 29263854 Free PMC article.

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