Balle T - Search Results

1

Synthetic Sansanmycin Analogues as Potent Mycobacterium tuberculosis Translocase I Inhibitors.

Tran W, Kusay AS, Hawkins PME, Cheung CY, Nagalingam G, Pujari V, Ford DJ, Stoye A, Ochoa JL, Audette RE, Hortle E, Oehlers SH, Charman SA, Linington RG, Rubin EJ, Dowson CG, Roper DI, Crick DC, Balle T, Cook GM, Britton WJ, Payne RJ. Tran W, et al. Among authors: balle t. J Med Chem. 2021 Dec 9;64(23):17326-17345. doi: 10.1021/acs.jmedchem.1c01407. Epub 2021 Nov 30. J Med Chem. 2021. PMID: 34845906

2

Synthesis and pharmacological evaluation of 6-aminonicotinic acid analogues as novel GABA(A) receptor agonists.

Petersen JG, Sørensen T, Damgaard M, Nielsen B, Jensen AA, Balle T, Bergmann R, Frølund B. Petersen JG, et al. Among authors: balle t. Eur J Med Chem. 2014 Sep 12;84:404-16. doi: 10.1016/j.ejmech.2014.07.039. Epub 2014 Jul 11. Eur J Med Chem. 2014. PMID: 25038482

3

Heterologous expression of concatenated nicotinic ACh receptors: Pros and cons of subunit concatenation and recommendations for construct designs.

Liao VWY, Kusay AS, Balle T, Ahring PK. Liao VWY, et al. Among authors: balle t. Br J Pharmacol. 2020 Sep;177(18):4275-4295. doi: 10.1111/bph.15188. Epub 2020 Aug 5. Br J Pharmacol. 2020. PMID: 32627170 Free PMC article.

4

Delta-containing GABA_A receptors in pain management: Promising targets for novel analgesics.

Luo Y, Kusay AS, Jiang T, Chebib M, Balle T. Luo Y, et al. Among authors: balle t. Neuropharmacology. 2021 Sep 1;195:108675. doi: 10.1016/j.neuropharm.2021.108675. Epub 2021 Jun 18. Neuropharmacology. 2021. PMID: 34153311 Review.

5

Novel methyllycaconitine analogues selective for the α4β2 over α7 nicotinic acetylcholine receptors.

Gallagher R, Qudah T, Balle T, Chebib M, McLeod MD. Gallagher R, et al. Among authors: balle t. Bioorg Med Chem. 2021 Dec 1;51:116516. doi: 10.1016/j.bmc.2021.116516. Epub 2021 Nov 10. Bioorg Med Chem. 2021. PMID: 34798380

6

Novel acetylcholine and carbamoylcholine analogues: development of a functionally selective alpha4beta2 nicotinic acetylcholine receptor agonist.

Hansen CP, Jensen AA, Christensen JK, Balle T, Liljefors T, Frølund B. Hansen CP, et al. Among authors: balle t. J Med Chem. 2008 Dec 11;51(23):7380-95. doi: 10.1021/jm701625v. J Med Chem. 2008. PMID: 18989912

7

Novel 4-(piperidin-4-yl)-1-hydroxypyrazoles as gamma-aminobutyric acid(A) receptor ligands: synthesis, pharmacology, and structure-activity relationships.

Møller HA, Sander T, Kristensen JL, Nielsen B, Krall J, Bergmann ML, Christiansen B, Balle T, Jensen AA, Frølund B. Møller HA, et al. Among authors: balle t. J Med Chem. 2010 Apr 22;53(8):3417-21. doi: 10.1021/jm100106r. J Med Chem. 2010. PMID: 20355712

8

Synthesis and biological evaluation of 4-(aminomethyl)-1-hydroxypyrazole analogues of muscimol as γ-aminobutyric acid(a) receptor agonists.

Petersen JG, Bergmann R, Møller HA, Jørgensen CG, Nielsen B, Kehler J, Frydenvang K, Kristensen J, Balle T, Jensen AA, Kristiansen U, Frølund B. Petersen JG, et al. Among authors: balle t. J Med Chem. 2013 Feb 14;56(3):993-1006. doi: 10.1021/jm301473k. Epub 2013 Jan 23. J Med Chem. 2013. PMID: 23294161

9

Exploring the orthosteric binding site of the γ-aminobutyric acid type A receptor using 4-(Piperidin-4-yl)-1-hydroxypyrazoles 3- or 5-imidazolyl substituted: design, synthesis, and pharmacological evaluation.

Krall J, Jensen CH, Sørensen TE, Nielsen B, Jensen AA, Sander T, Balle T, Frølund B. Krall J, et al. Among authors: balle t. J Med Chem. 2013 Aug 22;56(16):6536-40. doi: 10.1021/jm4006466. Epub 2013 Aug 8. J Med Chem. 2013. PMID: 23855889

10

Covalent trapping of methyllycaconitine at the α4-α4 interface of the α4β2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed.

Absalom NL, Quek G, Lewis TM, Qudah T, von Arenstorff I, Ambrus JI, Harpsøe K, Karim N, Balle T, McLeod MD, Chebib M. Absalom NL, et al. Among authors: balle t. J Biol Chem. 2013 Sep 13;288(37):26521-32. doi: 10.1074/jbc.M113.475053. Epub 2013 Jul 26. J Biol Chem. 2013. PMID: 23893416 Free PMC article.

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