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Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdown.
iScience. 2021 Oct 28;24(11):103366. doi: 10.1016/j.isci.2021.103366. eCollection 2021 Nov 19.
iScience. 2021.
PMID: 34825138
Free PMC article.
Metabolic reprograming of antioxidant defense: a precision medicine perspective for radiotherapy of lung cancer?
Matschke J, Larafa S, Jendrossek V.
Matschke J, et al. Among authors: larafa s.
Biochem Soc Trans. 2021 Jun 30;49(3):1265-1277. doi: 10.1042/BST20200866.
Biochem Soc Trans. 2021.
PMID: 34110407
Review.
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Targeting AKT-Dependent Regulation of Antioxidant Defense Sensitizes AKT-E17K Expressing Cancer Cells to Ionizing Radiation.
Goetting I, Larafa S, Eul K, Kunin M, Jakob B, Matschke J, Jendrossek V.
Goetting I, et al. Among authors: larafa s.
Front Oncol. 2022 Jul 8;12:920017. doi: 10.3389/fonc.2022.920017. eCollection 2022.
Front Oncol. 2022.
PMID: 35875130
Free PMC article.
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Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction.
Henning Y, Blind US, Larafa S, Matschke J, Fandrey J.
Henning Y, et al. Among authors: larafa s.
Cell Death Dis. 2022 Jul 29;13(7):662. doi: 10.1038/s41419-022-05121-z.
Cell Death Dis. 2022.
PMID: 35906211
Free PMC article.
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Cigarette smoke causes a bioenergetic crisis in RPE cells involving the downregulation of HIF-1α under normoxia.
Henning Y, Willbrand K, Larafa S, Weißenberg G, Matschke V, Theiss C, Görtz GE, Matschke J.
Henning Y, et al. Among authors: larafa s.
Cell Death Discov. 2023 Oct 25;9(1):398. doi: 10.1038/s41420-023-01695-5.
Cell Death Discov. 2023.
PMID: 37880219
Free PMC article.
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α-Ketoglutarate supplementation and NAD+ modulation enhance metabolic rewiring and radiosensitization in SLC25A1 inhibited cancer cells.
Xiang K, Kunin M, Larafa S, Busch M, Dünker N, Jendrossek V, Matschke J.
Xiang K, et al. Among authors: larafa s.
Cell Death Discov. 2024 Jan 15;10(1):27. doi: 10.1038/s41420-024-01805-x.
Cell Death Discov. 2024.
PMID: 38225236
Free PMC article.
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