Herzog RW - Search Results

1

Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models.

Hakim CH, Kumar SRP, Pérez-López DO, Wasala NB, Zhang D, Yue Y, Teixeira J, Pan X, Zhang K, Million ED, Nelson CE, Metzger S, Han J, Louderman JA, Schmidt F, Feng F, Grimm D, Smith BF, Yao G, Yang NN, Gersbach CA, Chen SJ, Herzog RW, Duan D. Hakim CH, et al. Among authors: herzog rw. Nat Commun. 2021 Nov 24;12(1):6769. doi: 10.1038/s41467-021-26830-7. Nat Commun. 2021. PMID: 34819506 Free PMC article.

2

Clinical development of gene therapy: results and lessons from recent successes.

Kumar SR, Markusic DM, Biswas M, High KA, Herzog RW. Kumar SR, et al. Among authors: herzog rw. Mol Ther Methods Clin Dev. 2016 May 25;3:16034. doi: 10.1038/mtm.2016.34. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27257611 Free PMC article. Review.

3

The Balance between CD8⁺ T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose.

Kumar SRP, Hoffman BE, Terhorst C, de Jong YP, Herzog RW. Kumar SRP, et al. Among authors: herzog rw. Mol Ther. 2017 Apr 5;25(4):880-891. doi: 10.1016/j.ymthe.2017.02.014. Epub 2017 Mar 9. Mol Ther. 2017. PMID: 28284982 Free PMC article.

4

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8⁺ T cells.

Rogers GL, Shirley JL, Zolotukhin I, Kumar SRP, Sherman A, Perrin GQ, Hoffman BE, Srivastava A, Basner-Tschakarjan E, Wallet MA, Terhorst C, Biswas M, Herzog RW. Rogers GL, et al. Among authors: herzog rw. Blood. 2017 Jun 15;129(24):3184-3195. doi: 10.1182/blood-2016-11-751040. Epub 2017 May 3. Blood. 2017. PMID: 28468798 Free PMC article.

5

Immune Modulatory Cell Therapy for Hemophilia B Based on CD20-Targeted Lentiviral Gene Transfer to Primary B Cells.

Wang X, Herzog RW, Byrne BJ, Kumar SRP, Zhou Q, Buchholz CJ, Biswas M. Wang X, et al. Among authors: herzog rw. Mol Ther Methods Clin Dev. 2017 Mar 29;5:76-82. doi: 10.1016/j.omtm.2017.03.005. eCollection 2017 Jun 16. Mol Ther Methods Clin Dev. 2017. PMID: 28480307 Free PMC article.

6

Gene Therapy With Regulatory T Cells: A Beneficial Alliance.

Biswas M, Kumar SRP, Terhorst C, Herzog RW. Biswas M, et al. Among authors: herzog rw. Front Immunol. 2018 Mar 19;9:554. doi: 10.3389/fimmu.2018.00554. eCollection 2018. Front Immunol. 2018. PMID: 29616042 Free PMC article. Review.

7

Update on clinical gene therapy for hemophilia.

Perrin GQ, Herzog RW, Markusic DM. Perrin GQ, et al. Among authors: herzog rw. Blood. 2019 Jan 31;133(5):407-414. doi: 10.1182/blood-2018-07-820720. Epub 2018 Dec 17. Blood. 2019. PMID: 30559260 Free PMC article. Review.

8

AAV-Mediated Gene Delivery to the Liver: Overview of Current Technologies and Methods.

Palaschak B, Herzog RW, Markusic DM. Palaschak B, et al. Among authors: herzog rw. Methods Mol Biol. 2019;1950:333-360. doi: 10.1007/978-1-4939-9139-6_20. Methods Mol Biol. 2019. PMID: 30783984 Review.

9

TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer.

Butterfield JSS, Biswas M, Shirley JL, Kumar SRP, Sherman A, Terhorst C, Ling C, Herzog RW. Butterfield JSS, et al. Among authors: herzog rw. Hum Gene Ther Methods. 2019 Jun;30(3):81-92. doi: 10.1089/hgtb.2019.013. Hum Gene Ther Methods. 2019. PMID: 31140323 Free PMC article.

10

Role of Small Intestine and Gut Microbiome in Plant-Based Oral Tolerance for Hemophilia.

Kumar SRP, Wang X, Avuthu N, Bertolini TB, Terhorst C, Guda C, Daniell H, Herzog RW. Kumar SRP, et al. Among authors: herzog rw. Front Immunol. 2020 May 20;11:844. doi: 10.3389/fimmu.2020.00844. eCollection 2020. Front Immunol. 2020. PMID: 32508814 Free PMC article.

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