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NUAK family kinase 2 is a novel therapeutic target for prostate cancer.
Fu W, Zhao MT, Driver LM, Schirmer AU, Yin Q, You S, Freedland SJ, DiGiovanni J, Drewry DH, Macias E. Fu W, et al. Among authors: macias e. Mol Carcinog. 2022 Mar;61(3):334-345. doi: 10.1002/mc.23374. Epub 2021 Nov 24. Mol Carcinog. 2022. PMID: 34818445
Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer.
Schirmer AU, Driver LM, Zhao MT, Wells CI, Pickett JE, O'Bryne SN, Eduful BJ, Yang X, Howard L, You S, Devi GR, DiGiovanni J, Freedland SJ, Chi JT, Drewry DH, Macias E. Schirmer AU, et al. Among authors: macias e. Mol Ther. 2022 Jan 5;30(1):485-500. doi: 10.1016/j.ymthe.2021.08.029. Epub 2021 Aug 25. Mol Ther. 2022. PMID: 34450249 Free PMC article.
CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.
Alfaqih MA, Nelson ER, Liu W, Safi R, Jasper JS, Macias E, Geradts J, Thompson JW, Dubois LG, Freeman MR, Chang CY, Chi JT, McDonnell DP, Freedland SJ. Alfaqih MA, et al. Among authors: macias e. Cancer Res. 2017 Apr 1;77(7):1662-1673. doi: 10.1158/0008-5472.CAN-16-2738. Epub 2017 Jan 27. Cancer Res. 2017. PMID: 28130224 Free PMC article.
27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6-JAK-STAT3 Signaling in Prostate Cancer Cells.
Dambal S, Alfaqih M, Sanders S, Maravilla E, Ramirez-Torres A, Galvan GC, Reis-Sobreiro M, Rotinen M, Driver LM, Behrove MS, Talisman TJ, Yoon J, You S, Turkson J, Chi JT, Freeman MR, Macias E, Freedland SJ. Dambal S, et al. Among authors: macias e. Mol Cancer Res. 2020 May;18(5):671-684. doi: 10.1158/1541-7786.MCR-19-0974. Epub 2020 Feb 4. Mol Cancer Res. 2020. PMID: 32019810 Free PMC article.
Angiotensin receptor signaling and prostate tumor growth in mice.
Scott-Emuakpor J, Allot E, Johnson SA, Howard LE, Macias E, Freedland SJ, Gurley SB. Scott-Emuakpor J, et al. Among authors: macias e. J Exp Ther Oncol. 2017 Sep;11(2):107-115. J Exp Ther Oncol. 2017. PMID: 28976133 Free PMC article.
Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model.
Masko EM, Alfaqih MA, Solomon KR, Barry WT, Newgard CB, Muehlbauer MJ, Valilis NA, Phillips TE, Poulton SH, Freedland AR, Sun S, Dambal SK, Sanders SE, Macias E, Freeman MR, Dewhirst MW, Pizzo SV, Freedland SJ. Masko EM, et al. Among authors: macias e. Prostate. 2017 Apr;77(5):446-457. doi: 10.1002/pros.23282. Epub 2016 Nov 30. Prostate. 2017. PMID: 27900797 Free PMC article.
176 results