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ERK5 Inhibition Induces Autophagy-Mediated Cancer Cell Death by Activating ER Stress.
Front Cell Dev Biol. 2021 Nov 4;9:742049. doi: 10.3389/fcell.2021.742049. eCollection 2021.
Front Cell Dev Biol. 2021.
PMID: 34805151
Free PMC article.
The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells.
Muñoz-Guardiola P, Casas J, Megías-Roda E, Solé S, Perez-Montoyo H, Yeste-Velasco M, Erazo T, Diéguez-Martínez N, Espinosa-Gil S, Muñoz-Pinedo C, Yoldi G, Abad JL, Segura MF, Moran T, Romeo M, Bosch-Barrera J, Oaknin A, Alfón J, Domènech C, Fabriàs G, Velasco G, Lizcano JM.
Muñoz-Guardiola P, et al. Among authors: espinosa gil s.
Autophagy. 2021 Jun;17(6):1349-1366. doi: 10.1080/15548627.2020.1761651. Epub 2020 May 25.
Autophagy. 2021.
PMID: 32397857
Free PMC article.
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SUMOylation Is Required for ERK5 Nuclear Translocation and ERK5-Mediated Cancer Cell Proliferation.
Erazo T, Espinosa-Gil S, Diéguez-Martínez N, Gómez N, Lizcano JM.
Erazo T, et al. Among authors: espinosa gil s.
Int J Mol Sci. 2020 Mar 23;21(6):2203. doi: 10.3390/ijms21062203.
Int J Mol Sci. 2020.
PMID: 32209980
Free PMC article.
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The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival.
Diéguez-Martínez N, Espinosa-Gil S, Yoldi G, Megías-Roda E, Bolinaga-Ayala I, Viñas-Casas M, Gorgisen G, Domingo-Ortí I, Pérez-Montoyo H, Bayascas JR, Colas E, Dolcet X, Lizcano JM.
Diéguez-Martínez N, et al. Among authors: espinosa gil s.
Cell Mol Life Sci. 2022 Sep 19;79(10):524. doi: 10.1007/s00018-022-04541-6.
Cell Mol Life Sci. 2022.
PMID: 36123565
Free PMC article.
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STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.
Granado-Martínez P, Garcia-Ortega S, González-Sánchez E, McGrail K, Selgas R, Grueso J, Gil R, Naldaiz-Gastesi N, Rhodes AC, Hernandez-Losa J, Ferrer B, Canals F, Villanueva J, Méndez O, Espinosa-Gil S, Lizcano JM, Muñoz-Couselo E, García-Patos V, Recio JA.
Granado-Martínez P, et al. Among authors: espinosa gil s.
Commun Biol. 2020 Jul 9;3(1):366. doi: 10.1038/s42003-020-1092-0.
Commun Biol. 2020.
PMID: 32647375
Free PMC article.
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MAP kinase ERK5 modulates cancer cell sensitivity to extrinsic apoptosis induced by death-receptor agonists.
Espinosa-Gil S, Ivanova S, Alari-Pahissa E, Denizli M, Villafranca-Magdalena B, Viñas-Casas M, Bolinaga-Ayala I, Gámez-García A, Faundez-Vidiella C, Colas E, Lopez-Botet M, Zorzano A, Lizcano JM.
Espinosa-Gil S, et al.
Cell Death Dis. 2023 Nov 2;14(11):715. doi: 10.1038/s41419-023-06229-6.
Cell Death Dis. 2023.
PMID: 37919293
Free PMC article.
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