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Cancer cells hijack T-cell mitochondria.
Baldwin JG, Gattinoni L. Baldwin JG, et al. Among authors: gattinoni l. Nat Nanotechnol. 2022 Jan;17(1):3-4. doi: 10.1038/s41565-021-01006-y. Nat Nanotechnol. 2022. PMID: 34795442 No abstract available.
An engineered IL-2 partial agonist promotes CD8+ T cell stemness.
Mo F, Yu Z, Li P, Oh J, Spolski R, Zhao L, Glassman CR, Yamamoto TN, Chen Y, Golebiowski FM, Hermans D, Majri-Morrison S, Picton LK, Liao W, Ren M, Zhuang X, Mitra S, Lin JX, Gattinoni L, Powell JD, Restifo NP, Garcia KC, Leonard WJ. Mo F, et al. Among authors: gattinoni l. Nature. 2021 Sep;597(7877):544-548. doi: 10.1038/s41586-021-03861-0. Epub 2021 Sep 15. Nature. 2021. PMID: 34526724 Free PMC article.
c-Myb redefines the hierarchy of stem-like T cells.
Heuser C, Gattinoni L. Heuser C, et al. Among authors: gattinoni l. Nat Immunol. 2022 Oct;23(10):1405-1407. doi: 10.1038/s41590-022-01319-7. Nat Immunol. 2022. PMID: 36192534 No abstract available.
Nanowires engineer naive T cells for immunotherapy.
Slavkovic-Lukic D, Gattinoni L. Slavkovic-Lukic D, et al. Among authors: gattinoni l. Nat Nanotechnol. 2024 May 27. doi: 10.1038/s41565-024-01651-z. Online ahead of print. Nat Nanotechnol. 2024. PMID: 38802668 No abstract available.
International Regensburg Center for Interventional Immunology (RCI) symposium on "Synthetic immunology and environment-adapted redirection of T cells", 17-18 July, 2019, Regensburg, Germany.
Beckhove P, Edinger M, Feuerer M, Gattinoni L, Abken H. Beckhove P, et al. Among authors: gattinoni l. Cancer Immunol Immunother. 2020 Apr;69(4):677-682. doi: 10.1007/s00262-019-02467-w. Epub 2020 Mar 2. Cancer Immunol Immunother. 2020. PMID: 32123937 Free PMC article. No abstract available.
BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells.
Yao C, Lou G, Sun HW, Zhu Z, Sun Y, Chen Z, Chauss D, Moseman EA, Cheng J, D'Antonio MA, Shi W, Shi J, Kometani K, Kurosaki T, Wherry EJ, Afzali B, Gattinoni L, Zhu Y, McGavern DB, O'Shea JJ, Schwartzberg PL, Wu T. Yao C, et al. Among authors: gattinoni l. Nat Immunol. 2021 Mar;22(3):370-380. doi: 10.1038/s41590-021-00868-7. Epub 2021 Feb 11. Nat Immunol. 2021. PMID: 33574619 Free PMC article.
The New Old CD8+ T Cells in the Immune Paradox of Pregnancy.
Hardardottir L, Bazzano MV, Glau L, Gattinoni L, Köninger A, Tolosa E, Solano ME. Hardardottir L, et al. Among authors: gattinoni l. Front Immunol. 2021 Nov 16;12:765730. doi: 10.3389/fimmu.2021.765730. eCollection 2021. Front Immunol. 2021. PMID: 34868016 Free PMC article. Review.
Synthetic soldiers: Turning T cells into immortal warriors.
Restifo NP, Gattinoni L. Restifo NP, et al. Among authors: gattinoni l. J Exp Med. 2024 May 6;221(5):e20240258. doi: 10.1084/jem.20240258. Epub 2024 Apr 18. J Exp Med. 2024. PMID: 38634804 Free article.
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate.
Ji Y, Fioravanti J, Zhu W, Wang H, Wu T, Hu J, Lacey NE, Gautam S, Le Gall JB, Yang X, Hocker JD, Escobar TM, He S, Dell'Orso S, Hawk NV, Kapoor V, Telford WG, Di Croce L, Muljo SA, Zhang Y, Sartorelli V, Gattinoni L. Ji Y, et al. Among authors: gattinoni l. Nat Commun. 2019 May 14;10(1):2157. doi: 10.1038/s41467-019-09882-8. Nat Commun. 2019. PMID: 31089138 Free PMC article.
Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity.
Hermans D, Gautam S, García-Cañaveras JC, Gromer D, Mitra S, Spolski R, Li P, Christensen S, Nguyen R, Lin JX, Oh J, Du N, Veenbergen S, Fioravanti J, Ebina-Shibuya R, Bleck C, Neckers LM, Rabinowitz JD, Gattinoni L, Leonard WJ. Hermans D, et al. Among authors: gattinoni l. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):6047-6055. doi: 10.1073/pnas.1920413117. Epub 2020 Mar 2. Proc Natl Acad Sci U S A. 2020. PMID: 32123114 Free PMC article.
670 results