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G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer.
Mukhopadhyay C, Yang C, Xu L, Liu D, Wang Y, Huang D, Deonarine LD, Cyrta J, Davicioni E, Sboner A, Robinson BD, Chinnaiyan AM, Rubin MA, Barbieri CE, Zhou P. Mukhopadhyay C, et al. Among authors: xu l. Nat Commun. 2021 Nov 18;12(1):6662. doi: 10.1038/s41467-021-27024-x. Nat Commun. 2021. PMID: 34795264 Free PMC article.
SPOP mutation leads to genomic instability in prostate cancer.
Boysen G, Barbieri CE, Prandi D, Blattner M, Chae SS, Dahija A, Nataraj S, Huang D, Marotz C, Xu L, Huang J, Lecca P, Chhangawala S, Liu D, Zhou P, Sboner A, de Bono JS, Demichelis F, Houvras Y, Rubin MA. Boysen G, et al. Among authors: xu l. Elife. 2015 Sep 16;4:e09207. doi: 10.7554/eLife.09207. Elife. 2015. PMID: 26374986 Free PMC article.
Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover.
Geng C, He B, Xu L, Barbieri CE, Eedunuri VK, Chew SA, Zimmermann M, Bond R, Shou J, Li C, Blattner M, Lonard DM, Demichelis F, Coarfa C, Rubin MA, Zhou P, O'Malley BW, Mitsiades N. Geng C, et al. Among authors: xu l. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6997-7002. doi: 10.1073/pnas.1304502110. Epub 2013 Apr 4. Proc Natl Acad Sci U S A. 2013. PMID: 23559371 Free PMC article.
Excessive interstitial free-water in cortical gray matter preceding accelerated volume changes in individuals at clinical high risk for psychosis.
Cho KIK, Zhang F, Penzel N, Seitz-Holland J, Tang Y, Zhang T, Xu L, Li H, Keshavan M, Whitfield-Gabrieli S, Niznikiewicz M, Stone WS, Wang J, Shenton ME, Pasternak O. Cho KIK, et al. Among authors: xu l. Mol Psychiatry. 2024 Jun 3. doi: 10.1038/s41380-024-02597-3. Online ahead of print. Mol Psychiatry. 2024. PMID: 38830974
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