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In vitro and in silico studies of chalcones derived from natural acetophenone inhibitors of NorA and MepA multidrug efflux pumps in Staphylococcus aureus.
Freitas TS, Xavier JC, Pereira RLS, Rocha JE, Campina FF, de Araújo Neto JB, Silva MMC, Barbosa CRS, Marinho ES, Nogueira CES, Dos Santos HS, Coutinho HDM, Teixeira AMR. Freitas TS, et al. Among authors: dos santos hs. Microb Pathog. 2021 Dec;161(Pt B):105286. doi: 10.1016/j.micpath.2021.105286. Epub 2021 Nov 16. Microb Pathog. 2021. PMID: 34793877
Structural and Microbiological Characterization of 5-Hydroxy-3,7,4'-Trimethoxyflavone: A Flavonoid Isolated from Vitex gardneriana Schauer Leaves.
Macedo I, da Silva JH, da Silva PT, Cruz BG, do Vale JPC, Dos Santos HS, Bandeira PN, de Souza EB, Xavier MR, Coutinho HDM, Braz-Filho R, Teixeira AMR. Macedo I, et al. Among authors: dos santos hs. Microb Drug Resist. 2019 Apr;25(3):434-438. doi: 10.1089/mdr.2018.0359. Epub 2019 Feb 11. Microb Drug Resist. 2019. PMID: 30741597
Evaluation of antibacterial and enhancement of antibiotic action by the flavonoid kaempferol 7-O-β-D-(6″-O-cumaroyl)-glucopyranoside isolated from Croton piauhiensis müll.
Cruz BG, Dos Santos HS, Bandeira PN, Rodrigues THS, Matos MGC, Nascimento MF, de Carvalho GGC, Braz-Filho R, Teixeira AMR, Tintino SR, Coutinho HDM. Cruz BG, et al. Among authors: dos santos hs. Microb Pathog. 2020 Jun;143:104144. doi: 10.1016/j.micpath.2020.104144. Epub 2020 Mar 17. Microb Pathog. 2020. PMID: 32194182
Direct antibacterial and antibiotic resistance modulatory activity of chalcones synthesized from the natural product 2-hydroxy-3,4,6-trimethoxyacetophenone.
Freitas TS, Xavier JDC, Pereira RLS, Rocha JE, Muniz DF, da Silva PT, da Hora JP, Dos Santos HS, Bandeira PN, Nogueira CES, Teixeira AMR, Coutinho HDM. Freitas TS, et al. Among authors: dos santos hs. FEMS Microbiol Lett. 2020 Aug 1;367(15):fnaa124. doi: 10.1093/femsle/fnaa124. FEMS Microbiol Lett. 2020. PMID: 32756951
Antinociceptive effect of triterpene acetyl aleuritolic acid isolated from Croton zehntneri in adult zebrafish (Danio rerio).
Bezerra AJN, Silva FCO, da Silva AW, Ferreira MKA, Marinho EM, Marinho MM, Magalhães FEA, Bandeira PN, Rodrigues Teixeira AM, Marinho ES, de Menezes JESA, Dos Santos HS. Bezerra AJN, et al. Among authors: dos santos hs. Biochem Biophys Res Commun. 2021 Jan 1;534:478-484. doi: 10.1016/j.bbrc.2020.11.056. Epub 2020 Nov 28. Biochem Biophys Res Commun. 2021. PMID: 33261884
Chalcones reverse the anxiety and convulsive behavior of adult zebrafish.
Ferreira MKA, da Silva AW, Dos Santos Moura AL, Sales KVB, Marinho EM, do Nascimento Martins Cardoso J, Marinho MM, Bandeira PN, Magalhães FEA, Marinho ES, de Menezes JESA, Dos Santos HS. Ferreira MKA, et al. Among authors: dos santos moura al, dos santos hs. Epilepsy Behav. 2021 Apr;117:107881. doi: 10.1016/j.yebeh.2021.107881. Epub 2021 Mar 9. Epilepsy Behav. 2021. PMID: 33711684
Anxiolytic-like effect of brominated compounds from the marine sponge Aplysina fulva on adult zebrafish (Danio rerio): Involvement of the GABAergic system.
de F Cesário HPS, Silva FCO, Ferreira MKA, de Menezes JESA, Dos Santos HS, Nogueira CES, de L Silva KSB, Hajdu E, Silveira ER, Pessoa ODL. de F Cesário HPS, et al. Among authors: dos santos hs. Neurochem Int. 2021 Jun;146:105021. doi: 10.1016/j.neuint.2021.105021. Epub 2021 Mar 16. Neurochem Int. 2021. PMID: 33741413
Evaluation of Antimicrobial and Antioxidant Potential of Essential Oil from Croton piauhiensis Müll. Arg.
do Vale JPC, Vasconcelos MA, Arruda FVS, Firmino NCS, Pereira AL, Andrade AL, Saker-Sampaio S, Sampaio AH, Marinho ES, Teixeira AMR, Marinho MM, Rodrigues THS, Teixeira EH, Dos Santos HS. do Vale JPC, et al. Among authors: dos santos hs. Curr Microbiol. 2021 May;78(5):1926-1938. doi: 10.1007/s00284-021-02449-1. Epub 2021 Mar 29. Curr Microbiol. 2021. PMID: 33782740
Chemical composition and potentiating action of Norfloxacin mediated by the essential oil of Piper caldense C.D.C. against Staphylococcus aureus strains overexpressing efflux pump genes.
Leal ALAB, Bezerra CF, Confortin C, da Silva LE, Marinho EM, Marinho MM, Vasconcelos MA, da Silva TG, Marinho ES, Teixeira AMR, Coutinho HDM, Barreto HM, Dos Santos HS. Leal ALAB, et al. Among authors: dos santos hs. Arch Microbiol. 2021 Sep;203(7):4727-4736. doi: 10.1007/s00203-021-02393-5. Epub 2021 May 29. Arch Microbiol. 2021. PMID: 34052872 Free PMC article.
Antibacterial and antibiotic modifying activity, ADMET study and molecular docking of synthetic chalcone (E)-1-(2-hydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps.
Rocha JE, de Freitas TS, da Cunha Xavier J, Pereira RLS, Junior FNP, Nogueira CES, Marinho MM, Bandeira PN, de Oliveira MR, Marinho ES, Teixeira AMR, Dos Santos HS, Coutinho HDM. Rocha JE, et al. Among authors: dos santos hs. Biomed Pharmacother. 2021 Aug;140:111768. doi: 10.1016/j.biopha.2021.111768. Epub 2021 May 28. Biomed Pharmacother. 2021. PMID: 34058442 Free article.
83 results