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Page 1
TLR9 plus STING Agonist Adjuvant Combination Induces Potent Neopeptide T Cell Immunity and Improves Immune Checkpoint Blockade Efficacy in a Tumor Model.
Castro Eiro MD, Hioki K, Li L, Wilmsen MEP, Kiernan CH, Brouwers-Haspels I, van Meurs M, Zhao M, de Wit H, Grashof DGB, van de Werken HJG, Mueller YM, Schliehe C, Temizoz B, Kobiyama K, Ishii KJ, Katsikis PD. Castro Eiro MD, et al. Among authors: grashof dgb. J Immunol. 2024 Feb 1;212(3):455-465. doi: 10.4049/jimmunol.2300038. J Immunol. 2024. PMID: 38063488 Free PMC article.
Ibrutinib directly reduces CD8+T cell exhaustion independent of BTK.
Li L, Zhao M, Kiernan CH, Castro Eiro MD, van Meurs M, Brouwers-Haspels I, Wilmsen MEP, Grashof DGB, van de Werken HJG, Hendriks RW, Mueller YM, Katsikis PD. Li L, et al. Among authors: grashof dgb. Front Immunol. 2023 Sep 12;14:1201415. doi: 10.3389/fimmu.2023.1201415. eCollection 2023. Front Immunol. 2023. PMID: 37771591 Free PMC article.
Trained Immunity in Primary Sjögren's Syndrome: Linking Type I Interferons to a Pro-Atherogenic Phenotype.
Huijser E, van Helden-Meeuwsen CG, Grashof DGB, Tarn JR, Brkic Z, Huisman JMA, Wahadat MJ, van de Werken HJG, Lopes AP, van Roon JAG, van Daele PLA, Kamphuis S, Ng WF, Bekkering S, Joosten LAB, Dik WA, Versnel MA. Huijser E, et al. Among authors: grashof dgb. Front Immunol. 2022 Jul 4;13:840751. doi: 10.3389/fimmu.2022.840751. eCollection 2022. Front Immunol. 2022. PMID: 35860283 Free PMC article.
Stratification of hospitalized COVID-19 patients into clinical severity progression groups by immuno-phenotyping and machine learning.
Mueller YM, Schrama TJ, Ruijten R, Schreurs MWJ, Grashof DGB, van de Werken HJG, Lasinio GJ, Álvarez-Sierra D, Kiernan CH, Castro Eiro MD, van Meurs M, Brouwers-Haspels I, Zhao M, Li L, de Wit H, Ouzounis CA, Wilmsen MEP, Alofs TM, Laport DA, van Wees T, Kraker G, Jaimes MC, Van Bockstael S, Hernández-González M, Rokx C, Rijnders BJA, Pujol-Borrell R, Katsikis PD. Mueller YM, et al. Among authors: grashof dgb. Nat Commun. 2022 Feb 17;13(1):915. doi: 10.1038/s41467-022-28621-0. Nat Commun. 2022. PMID: 35177626 Free PMC article.
Hyperresponsive cytosolic DNA-sensing pathway in monocytes from primary Sjögren's syndrome.
Huijser E, Bodewes ILA, Lourens MS, van Helden-Meeuwsen CG, van den Bosch TPP, Grashof DGB, van de Werken HJG, Lopes AP, van Roon JAG, van Daele PLA, Brkic Z, Dik WA, Versnel MA. Huijser E, et al. Among authors: grashof dgb. Rheumatology (Oxford). 2022 Aug 3;61(8):3491-3496. doi: 10.1093/rheumatology/keac016. Rheumatology (Oxford). 2022. PMID: 35022662 Free PMC article.