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Hydrogen peroxide signaling via its transformation to a stereospecific alkyl hydroperoxide that escapes reductive inactivation.
Nat Commun. 2021 Nov 16;12(1):6626. doi: 10.1038/s41467-021-26991-5.
Nat Commun. 2021.
PMID: 34785665
Free PMC article.
Cysteine trisulfide oxidizes protein thiols and induces electrophilic stress in human cells.
Switzer CH, Guttzeit S, Eykyn TR, Eaton P.
Switzer CH, et al. Among authors: guttzeit s.
Redox Biol. 2021 Nov;47:102155. doi: 10.1016/j.redox.2021.102155. Epub 2021 Sep 29.
Redox Biol. 2021.
PMID: 34607161
Free PMC article.
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Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I.
Kamynina A, Guttzeit S, Eaton P, Cuello F.
Kamynina A, et al. Among authors: guttzeit s.
Hypertension. 2022 May;79(5):946-956. doi: 10.1161/HYPERTENSIONAHA.122.18756. Epub 2022 Feb 16.
Hypertension. 2022.
PMID: 35168371
Free article.
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A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation.
Charles RL, Abis G, Fernandez BF, Guttzeit S, Buccafusca R, Conte MR, Eaton P.
Charles RL, et al. Among authors: guttzeit s.
Redox Biol. 2021 Oct;46:102107. doi: 10.1016/j.redox.2021.102107. Epub 2021 Aug 18.
Redox Biol. 2021.
PMID: 34509915
Free PMC article.
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Post-translational modifications talk and crosstalk to class IIa histone deacetylases.
Guttzeit S, Backs J.
Guttzeit S, et al.
J Mol Cell Cardiol. 2022 Jan;162:53-61. doi: 10.1016/j.yjmcc.2021.08.007. Epub 2021 Aug 17.
J Mol Cell Cardiol. 2022.
PMID: 34416247
Review.
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