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Antisense Oligonucleotide-Mediated Splice Switching: Potential Therapeutic Approach for Cancer Mitigation.
Cancers (Basel). 2021 Nov 5;13(21):5555. doi: 10.3390/cancers13215555.
Cancers (Basel). 2021.
PMID: 34771719
Free PMC article.
Review.
Antisense Oligonucleotides Targeting Angiogenic Factors as Potential Cancer Therapeutics.
Le BT, Raguraman P, Kosbar TR, Fletcher S, Wilton SD, Veedu RN.
Le BT, et al. Among authors: raguraman p.
Mol Ther Nucleic Acids. 2019 Mar 1;14:142-157. doi: 10.1016/j.omtn.2018.11.007. Epub 2018 Nov 20.
Mol Ther Nucleic Acids. 2019.
PMID: 30594893
Free PMC article.
Review.
Item in Clipboard
Alpha-l-Locked Nucleic Acid-Modified Antisense Oligonucleotides Induce Efficient Splice Modulation In Vitro.
Raguraman P, Wang T, Ma L, Jørgensen PT, Wengel J, Veedu RN.
Raguraman P, et al.
Int J Mol Sci. 2020 Mar 31;21(7):2434. doi: 10.3390/ijms21072434.
Int J Mol Sci. 2020.
PMID: 32244535
Free PMC article.
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Phosphorothioate modification improves exon-skipping of antisense oligonucleotides based on sulfonyl phosphoramidates in mdx mouse myotubes.
Su Y, Raguraman P, Veedu RN, Filichev VV.
Su Y, et al. Among authors: raguraman p.
Org Biomol Chem. 2022 May 11;20(18):3790-3797. doi: 10.1039/d2ob00304j.
Org Biomol Chem. 2022.
PMID: 35438707
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Oligonucleotides containing 2'-O-methyl-5-(1-phenyl-1,2,3-triazol-4-yl)uridines demonstrate increased affinity for RNA and induce exon-skipping in vitro.
Gimenez Molina A, Raguraman P, Delcomyn L, Veedu RN, Nielsen P.
Gimenez Molina A, et al. Among authors: raguraman p.
Bioorg Med Chem. 2022 Feb 1;55:116559. doi: 10.1016/j.bmc.2021.116559. Epub 2021 Dec 12.
Bioorg Med Chem. 2022.
PMID: 34999527
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Splice-Switching Antisense Oligonucleotides Targeting Extra- and Intracellular Domains of Epidermal Growth Factor Receptor in Cancer Cells.
Balachandran AA, Raguraman P, Rahimizadeh K, Veedu RN.
Balachandran AA, et al. Among authors: raguraman p.
Biomedicines. 2023 Dec 13;11(12):3299. doi: 10.3390/biomedicines11123299.
Biomedicines. 2023.
PMID: 38137520
Free PMC article.
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Expediting dynamics approach to understand the influence of 14-3-3ζ causing metastatic cancer through the interaction of YAP1 and β-TRCP.
D K, Ramireddy S, P R, C S.
D K, et al. Among authors: p r.
Mol Biosyst. 2017 Sep 26;13(10):1981-1992. doi: 10.1039/c7mb00271h.
Mol Biosyst. 2017.
PMID: 28745364
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