Sakaki T - Search Results

1

Development of In Vitro and In Vivo Evaluation Systems for Vitamin D Derivatives and Their Application to Drug Discovery.

Yasuda K, Nishikawa M, Mano H, Takano M, Kittaka A, Ikushiro S, Sakaki T. Yasuda K, et al. Among authors: sakaki t. Int J Mol Sci. 2021 Oct 31;22(21):11839. doi: 10.3390/ijms222111839. Int J Mol Sci. 2021. PMID: 34769269 Free PMC article. Review.

2

Metabolism of 20-epimer of 1alpha,25-dihydroxyvitamin D3 by CYP24: species-based difference between humans and rats.

Kusudo T, Sakaki T, Abe D, Fujishima T, Kittaka A, Takayama H, Ohta M, Inouye K. Kusudo T, et al. Among authors: sakaki t. Biochem Biophys Res Commun. 2003 Oct 3;309(4):885-92. doi: 10.1016/j.bbrc.2003.08.097. Biochem Biophys Res Commun. 2003. PMID: 13679056

3

Sequential metabolism of 2,3,7-trichlorodibenzo-p-dioxin (2,3,7-triCDD) by cytochrome P450 and UDP-glucuronosyltransferase in human liver microsomes.

Kasai N, Sakaki T, Shinkyo R, Ikushiro S, Iyanagi T, Kamao M, Okano T, Ohta M, Inouye K. Kasai N, et al. Among authors: sakaki t. Drug Metab Dispos. 2004 Aug;32(8):870-5. doi: 10.1124/dmd.32.8.870. Drug Metab Dispos. 2004. PMID: 15258113

4

Metabolism of A-ring diastereomers of 1alpha,25-dihydroxyvitamin D3 by CYP24A1.

Kusudo T, Sakaki T, Abe D, Fujishima T, Kittaka A, Takayama H, Hatakeyama S, Ohta M, Inouye K. Kusudo T, et al. Among authors: sakaki t. Biochem Biophys Res Commun. 2004 Sep 3;321(4):774-82. doi: 10.1016/j.bbrc.2004.07.040. Biochem Biophys Res Commun. 2004. PMID: 15358094

5

Metabolism of 26,26,26,27,27,27-F6-1 alpha,23S,25-trihydroxyvitamin D3 by human UDP-glucuronosyltransferase 1A3.

Kasai N, Sakaki T, Shinkyo R, Ikushiro S, Iyanagi T, Ohta M, Inouye K. Kasai N, et al. Among authors: sakaki t. Drug Metab Dispos. 2005 Jan;33(1):102-7. doi: 10.1124/dmd.104.002303. Epub 2004 Oct 26. Drug Metab Dispos. 2005. PMID: 15507540

6

Metabolism of 2 alpha-propoxy-1 alpha,25-dihydroxyvitamin D3 and 2 alpha-(3-hydroxypropoxy)-1 alpha,25-dihydroxyvitamin D3 by human CYP27A1 and CYP24A1.

Abe D, Sakaki T, Kusudo T, Kittaka A, Saito N, Suhara Y, Fujishima T, Takayama H, Hamamoto H, Kamakura M, Ohta M, Inouye K. Abe D, et al. Among authors: sakaki t. Drug Metab Dispos. 2005 Jun;33(6):778-84. doi: 10.1124/dmd.104.003038. Epub 2005 Mar 11. Drug Metab Dispos. 2005. PMID: 15764712

7

Biodegradation of dioxins by recombinant Escherichia coli expressing rat CYP1A1 or its mutant.

Shinkyo R, Kamakura M, Ikushiro S, Inouye K, Sakaki T. Shinkyo R, et al. Among authors: sakaki t. Appl Microbiol Biotechnol. 2006 Sep;72(3):584-90. doi: 10.1007/s00253-005-0286-1. Epub 2006 Feb 18. Appl Microbiol Biotechnol. 2006. PMID: 16489453

8

Monospecific antipeptide antibodies against human hepatic UDP-glucuronosyltransferase 1A subfamily (UGT1A) isoforms.

Ikushiro S, Emi Y, Kato Y, Yamada S, Sakaki T. Ikushiro S, et al. Among authors: sakaki t. Drug Metab Pharmacokinet. 2006 Feb;21(1):70-4. doi: 10.2133/dmpk.21.70. Drug Metab Pharmacokinet. 2006. PMID: 16547396 Free article.

9

Interaction between mitochondrial CYP27B1 and adrenodoxin: role of arginine 458 of mouse CYP27B1.

Urushino N, Yamamoto K, Kagawa N, Ikushiro S, Kamakura M, Yamada S, Kato S, Inouye K, Sakaki T. Urushino N, et al. Among authors: sakaki t. Biochemistry. 2006 Apr 11;45(14):4405-12. doi: 10.1021/bi060072o. Biochemistry. 2006. PMID: 16584176

10

Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: amino acid residues responsible for species-based difference of CYP24A1 between humans and rats.

Hamamoto H, Kusudo T, Urushino N, Masuno H, Yamamoto K, Yamada S, Kamakura M, Ohta M, Inouye K, Sakaki T. Hamamoto H, et al. Among authors: sakaki t. Mol Pharmacol. 2006 Jul;70(1):120-8. doi: 10.1124/mol.106.023275. Epub 2006 Apr 14. Mol Pharmacol. 2006. PMID: 16617161

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