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1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development.
Wang T, Wang Z, de Fabritus L, Tao J, Saied EM, Lee HJ, Ramazanov BR, Jackson B, Burkhardt D, Parker M, Gleinich AS, Wang Z, Seo DE, Zhou T, Xu S, Alecu I, Azadi P, Arenz C, Hornemann T, Krishnaswamy S, van de Pavert SA, Kaech SM, Ivanova NB, Santori FR. Wang T, et al. Among authors: arenz c. Dev Cell. 2021 Nov 22;56(22):3128-3145.e15. doi: 10.1016/j.devcel.2021.10.018. Epub 2021 Nov 10. Dev Cell. 2021. PMID: 34762852 Free PMC article.
Small molecule inhibitors of ceramidases.
Saied EM, Arenz C. Saied EM, et al. Among authors: arenz c. Cell Physiol Biochem. 2014;34(1):197-212. doi: 10.1159/000362995. Epub 2014 Jun 16. Cell Physiol Biochem. 2014. PMID: 24977492 Free article. Review.
Inhibitors of Ceramidases.
Saied EM, Arenz C. Saied EM, et al. Among authors: arenz c. Chem Phys Lipids. 2016 May;197:60-8. doi: 10.1016/j.chemphyslip.2015.07.009. Epub 2015 Jul 26. Chem Phys Lipids. 2016. PMID: 26220616 Review.
Elucidating the chemical structure of native 1-deoxysphingosine.
Steiner R, Saied EM, Othman A, Arenz C, Maccarone AT, Poad BL, Blanksby SJ, von Eckardstein A, Hornemann T. Steiner R, et al. Among authors: arenz c. J Lipid Res. 2016 Jul;57(7):1194-203. doi: 10.1194/jlr.M067033. Epub 2016 May 10. J Lipid Res. 2016. PMID: 27165858 Free PMC article.
Structural insights into adiponectin receptors suggest ceramidase activity.
Vasiliauskaité-Brooks I, Sounier R, Rochaix P, Bellot G, Fortier M, Hoh F, De Colibus L, Bechara C, Saied EM, Arenz C, Leyrat C, Granier S. Vasiliauskaité-Brooks I, et al. Among authors: arenz c. Nature. 2017 Apr 6;544(7648):120-123. doi: 10.1038/nature21714. Epub 2017 Mar 22. Nature. 2017. PMID: 28329765 Free PMC article.
129 results