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1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development.
Wang T, Wang Z, de Fabritus L, Tao J, Saied EM, Lee HJ, Ramazanov BR, Jackson B, Burkhardt D, Parker M, Gleinich AS, Wang Z, Seo DE, Zhou T, Xu S, Alecu I, Azadi P, Arenz C, Hornemann T, Krishnaswamy S, van de Pavert SA, Kaech SM, Ivanova NB, Santori FR. Wang T, et al. Among authors: alecu i. Dev Cell. 2021 Nov 22;56(22):3128-3145.e15. doi: 10.1016/j.devcel.2021.10.018. Epub 2021 Nov 10. Dev Cell. 2021. PMID: 34762852 Free PMC article.
Neurotoxic 1-deoxysphingolipids and paclitaxel-induced peripheral neuropathy.
Kramer R, Bielawski J, Kistner-Griffin E, Othman A, Alecu I, Ernst D, Kornhauser D, Hornemann T, Spassieva S. Kramer R, et al. Among authors: alecu i. FASEB J. 2015 Nov;29(11):4461-72. doi: 10.1096/fj.15-272567. Epub 2015 Jul 21. FASEB J. 2015. PMID: 26198449 Free PMC article. Clinical Trial.
Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.
Alecu I, Tedeschi A, Behler N, Wunderling K, Lamberz C, Lauterbach MA, Gaebler A, Ernst D, Van Veldhoven PP, Al-Amoudi A, Latz E, Othman A, Kuerschner L, Hornemann T, Bradke F, Thiele C, Penno A. Alecu I, et al. J Lipid Res. 2017 Jan;58(1):42-59. doi: 10.1194/jlr.M068676. Epub 2016 Nov 23. J Lipid Res. 2017. PMID: 27881717 Free PMC article.
1-Deoxysphingolipids.
Lone MA, Santos T, Alecu I, Silva LC, Hornemann T. Lone MA, et al. Among authors: alecu i. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Apr;1864(4):512-521. doi: 10.1016/j.bbalip.2018.12.013. Epub 2019 Jan 6. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30625374 Review.
Oxidative stress increases 1-deoxysphingolipid levels in chronic kidney disease.
Gui T, Li Y, Zhang S, Alecu I, Chen Q, Zhao Y, Hornemann T, Kullak-Ublick GA, Gai Z. Gui T, et al. Among authors: alecu i. Free Radic Biol Med. 2021 Feb 20;164:139-148. doi: 10.1016/j.freeradbiomed.2021.01.011. Epub 2021 Jan 12. Free Radic Biol Med. 2021. PMID: 33450378 Free article.
45 results