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Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action.
Escher SE, Aguayo-Orozco A, Benfenati E, Bitsch A, Braunbeck T, Brotzmann K, Bois F, van der Burg B, Castel J, Exner T, Gadaleta D, Gardner I, Goldmann D, Hatley O, Golbamaki N, Graepel R, Jennings P, Limonciel A, Long A, Maclennan R, Mombelli E, Norinder U, Jain S, Capinha LS, Taboureau OT, Tolosa L, Vrijenhoek NG, van Vugt-Lussenburg BMA, Walker P, van de Water B, Wehr M, White A, Zdrazil B, Fisher C. Escher SE, et al. Among authors: walker p. Toxicol In Vitro. 2022 Mar;79:105269. doi: 10.1016/j.tiv.2021.105269. Epub 2021 Oct 29. Toxicol In Vitro. 2022. PMID: 34757180 Free article.
Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals.
van der Stel W, Carta G, Eakins J, Darici S, Delp J, Forsby A, Bennekou SH, Gardner I, Leist M, Danen EHJ, Walker P, van de Water B, Jennings P. van der Stel W, et al. Among authors: walker p. Arch Toxicol. 2020 Aug;94(8):2707-2729. doi: 10.1007/s00204-020-02792-5. Epub 2020 Jul 18. Arch Toxicol. 2020. PMID: 32607615 Free PMC article.
Correction to: Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals.
van der Stel W, Carta G, Eakins J, Darici S, Delp J, Forsby A, Bennekou SH, Gardner I, Leist M, Danen EHJ, Walker P, van de Water B, Jennings P. van der Stel W, et al. Among authors: walker p. Arch Toxicol. 2020 Aug;94(8):2731-2732. doi: 10.1007/s00204-020-02849-5. Arch Toxicol. 2020. PMID: 32720191 Free PMC article.
Comparing in vitro human liver models to in vivo human liver using RNA-Seq.
Gupta R, Schrooders Y, Hauser D, van Herwijnen M, Albrecht W, Ter Braak B, Brecklinghaus T, Castell JV, Elenschneider L, Escher S, Guye P, Hengstler JG, Ghallab A, Hansen T, Leist M, Maclennan R, Moritz W, Tolosa L, Tricot T, Verfaillie C, Walker P, van de Water B, Kleinjans J, Caiment F. Gupta R, et al. Among authors: walker p. Arch Toxicol. 2021 Feb;95(2):573-589. doi: 10.1007/s00204-020-02937-6. Epub 2020 Oct 27. Arch Toxicol. 2021. PMID: 33106934 Free PMC article.
Corrigendum to "Development of a generic zebrafish embryo PBPK model and application to the developmental toxicity assessment of valproic acid analogs" [Reprod. Toxicol. 93 (2020) 219⬜229].
Siméon S, Brotzmann K, Fisher C, Gardner I, Silvester S, Maclennan R, Walker P, Braunbeck T, Bois FY. Siméon S, et al. Among authors: walker p. Reprod Toxicol. 2020 Dec;98:300-303. doi: 10.1016/j.reprotox.2020.10.006. Epub 2020 Nov 3. Reprod Toxicol. 2020. PMID: 33153860 No abstract available.
New approach methods (NAMs) supporting read-across: Two neurotoxicity AOP-based IATA case studies.
Van der Stel W, Carta G, Eakins J, Delp J, Suciu I, Forsby A, Cediel-Ulloa A, Attoff K, Troger F, Kamp H, Gardner I, Zdrazil B, Moné MJ, Ecker GF, Pastor M, Gómez-Tamayo JC, White A, Danen EHJ, Leist M, Walker P, Jennings P, Hougaard Bennekou S, Van de Water B. Van der Stel W, et al. Among authors: walker p. ALTEX. 2021;38(4):615-635. doi: 10.14573/altex.2103051. Epub 2021 Jun 10. ALTEX. 2021. PMID: 34114044 Free article.
3,094 results