Schenk G - Search Results

1

LAM-1 from Lysobacter antibioticus: A potent zinc-dependent activity that inactivates β-lactam antibiotics.

Stroek R, Wilson L, Goracke W, Kang T, Vermue F, Krco S, Mendels Y, Douw A, Morris M, Knaven EG, Mitić N, Gutierrez MCR, Schenk EB, Clark A, Garcia D, Monteiro Pedroso M, Schenk G. Stroek R, et al. Among authors: schenk eb, schenk g. J Inorg Biochem. 2022 Jan;226:111637. doi: 10.1016/j.jinorgbio.2021.111637. Epub 2021 Oct 24. J Inorg Biochem. 2022. PMID: 34749064

2

Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase.

Schenk G, Gahan LR, Carrington LE, Mitic N, Valizadeh M, Hamilton SE, de Jersey J, Guddat LW. Schenk G, et al. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):273-8. doi: 10.1073/pnas.0407239102. Epub 2004 Dec 29. Proc Natl Acad Sci U S A. 2005. PMID: 15625111 Free PMC article.

3

Human tartrate-resistant acid phosphatase becomes an effective ATPase upon proteolytic activation.

Mitić N, Valizadeh M, Leung EW, de Jersey J, Hamilton S, Hume DA, Cassady AI, Schenk G. Mitić N, et al. Among authors: schenk g. Arch Biochem Biophys. 2005 Jul 15;439(2):154-64. doi: 10.1016/j.abb.2005.05.013. Arch Biochem Biophys. 2005. PMID: 15950921

4

Ca(II) Binding Regulates and Dominates the Reactivity of a Transition-Metal-Ion-Dependent Diesterase from Mycobacterium tuberculosis.

Pedroso MM, Larrabee JA, Ely F, Gwee SE, Mitić N, Ollis DL, Gahan LR, Schenk G. Pedroso MM, et al. Among authors: schenk g. Chemistry. 2016 Jan 18;22(3):999-1009. doi: 10.1002/chem.201504001. Epub 2015 Dec 14. Chemistry. 2016. PMID: 26662456

5

Promiscuous metallo-β-lactamases: MIM-1 and MIM-2 may play an essential role in quorum sensing networks.

Miraula M, Schenk G, Mitić N. Miraula M, et al. Among authors: schenk g. J Inorg Biochem. 2016 Sep;162:366-375. doi: 10.1016/j.jinorgbio.2015.12.014. Epub 2015 Dec 24. J Inorg Biochem. 2016. PMID: 26775612

6

AIM-1: An Antibiotic-Degrading Metallohydrolase That Displays Mechanistic Flexibility.

Selleck C, Larrabee JA, Harmer J, Guddat LW, Mitić N, Helweh W, Ollis DL, Craig WR, Tierney DL, Monteiro Pedroso M, Schenk G. Selleck C, et al. Among authors: schenk g. Chemistry. 2016 Dec 5;22(49):17704-17714. doi: 10.1002/chem.201602762. Epub 2016 Oct 25. Chemistry. 2016. PMID: 27778387

7

Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies.

Möhler JS, Kolmar T, Synnatschke K, Hergert M, Wilson LA, Ramu S, Elliott AG, Blaskovich MA, Sidjabat HE, Paterson DL, Schenk G, Cooper MA, Ziora ZM. Möhler JS, et al. Among authors: schenk g. J Inorg Biochem. 2017 Feb;167:134-141. doi: 10.1016/j.jinorgbio.2016.11.028. Epub 2016 Nov 24. J Inorg Biochem. 2017. PMID: 27984786

8

Insights into an evolutionary strategy leading to antibiotic resistance.

Hou CD, Liu JW, Collyer C, Mitić N, Pedroso MM, Schenk G, Ollis DL. Hou CD, et al. Among authors: schenk g. Sci Rep. 2017 Jan 11;7:40357. doi: 10.1038/srep40357. Sci Rep. 2017. PMID: 28074907 Free PMC article.

9

Visualization of the Reaction Trajectory and Transition State in a Hydrolytic Reaction Catalyzed by a Metalloenzyme.

Selleck C, Clayton D, Gahan LR, Mitić N, McGeary RP, Pedroso MM, Guddat LW, Schenk G. Selleck C, et al. Among authors: schenk g. Chemistry. 2017 Apr 6;23(20):4778-4781. doi: 10.1002/chem.201700866. Epub 2017 Mar 23. Chemistry. 2017. PMID: 28261912

10

Progress toward inhibitors of metallo-β-lactamases.

McGeary RP, Tan DT, Schenk G. McGeary RP, et al. Among authors: schenk g. Future Med Chem. 2017 May;9(7):673-691. doi: 10.4155/fmc-2017-0007. Epub 2017 May 15. Future Med Chem. 2017. PMID: 28504895 Review.

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