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Aberrant Phase Separation of FUS Leads to Lysosome Sequestering and Acidification.
Trnka F, Hoffmann C, Wang H, Sansevrino R, Rankovic B, Rost BR, Schmitz D, Schmidt HB, Milovanovic D. Trnka F, et al. Among authors: rost br. Front Cell Dev Biol. 2021 Oct 22;9:716919. doi: 10.3389/fcell.2021.716919. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34746121 Free PMC article.
A defect in the ionotropic glutamate receptor 6 gene (GRIK2) is associated with autosomal recessive mental retardation.
Motazacker MM, Rost BR, Hucho T, Garshasbi M, Kahrizi K, Ullmann R, Abedini SS, Nieh SE, Amini SH, Goswami C, Tzschach A, Jensen LR, Schmitz D, Ropers HH, Najmabadi H, Kuss AW. Motazacker MM, et al. Among authors: rost br. Am J Hum Genet. 2007 Oct;81(4):792-8. doi: 10.1086/521275. Epub 2007 Aug 31. Am J Hum Genet. 2007. PMID: 17847003 Free PMC article.
Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers.
Kaden D, Harmeier A, Weise C, Munter LM, Althoff V, Rost BR, Hildebrand PW, Schmitz D, Schaefer M, Lurz R, Skodda S, Yamamoto R, Arlt S, Finckh U, Multhaup G. Kaden D, et al. Among authors: rost br. EMBO Mol Med. 2012 Jul;4(7):647-59. doi: 10.1002/emmm.201200239. Epub 2012 Apr 19. EMBO Mol Med. 2012. PMID: 22514144 Free PMC article.
Optogenetic acidification of synaptic vesicles and lysosomes.
Rost BR, Schneider F, Grauel MK, Wozny C, Bentz C, Blessing A, Rosenmund T, Jentsch TJ, Schmitz D, Hegemann P, Rosenmund C. Rost BR, et al. Nat Neurosci. 2015 Dec;18(12):1845-1852. doi: 10.1038/nn.4161. Epub 2015 Nov 9. Nat Neurosci. 2015. PMID: 26551543 Free PMC article.
Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.
Kreye J, Wenke NK, Chayka M, Leubner J, Murugan R, Maier N, Jurek B, Ly LT, Brandl D, Rost BR, Stumpf A, Schulz P, Radbruch H, Hauser AE, Pache F, Meisel A, Harms L, Paul F, Dirnagl U, Garner C, Schmitz D, Wardemann H, Prüss H. Kreye J, et al. Among authors: rost br. Brain. 2016 Oct;139(Pt 10):2641-2652. doi: 10.1093/brain/aww208. Epub 2016 Aug 20. Brain. 2016. PMID: 27543972
RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.
Grauel MK, Maglione M, Reddy-Alla S, Willmes CG, Brockmann MM, Trimbuch T, Rosenmund T, Pangalos M, Vardar G, Stumpf A, Walter AM, Rost BR, Eickholt BJ, Haucke V, Schmitz D, Sigrist SJ, Rosenmund C. Grauel MK, et al. Among authors: rost br. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11615-11620. doi: 10.1073/pnas.1605256113. Epub 2016 Sep 26. Proc Natl Acad Sci U S A. 2016. PMID: 27671655 Free PMC article.
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