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Development and Implementation of In-House Pharmacogenomic Testing Program at a Major Academic Health System.
Mroz P, Michel S, Allen JD, Meyer T, McGonagle EJ, Carpentier R, Vecchia A, Schlichte A, Bishop JR, Dunnenberger HM, Yohe S, Thyagarajan B, Jacobson PA, Johnson SG. Mroz P, et al. Among authors: michel s. Front Genet. 2021 Oct 20;12:712602. doi: 10.3389/fgene.2021.712602. eCollection 2021. Front Genet. 2021. PMID: 34745204 Free PMC article. Review.
Next generation sequencing for clinical diagnostics: Five year experience of an academic laboratory.
Hartman P, Beckman K, Silverstein K, Yohe S, Schomaker M, Henzler C, Onsongo G, Lam HC, Munro S, Daniel J, Billstein B, Deshpande A, Hauge A, Mroz P, Lee W, Holle J, Wiens K, Karnuth K, Kemmer T, Leary M, Michel S, Pohlman L, Thayanithy V, Nelson A, Bower M, Thyagarajan B. Hartman P, et al. Among authors: michel s. Mol Genet Metab Rep. 2019 Mar 1;19:100464. doi: 10.1016/j.ymgmr.2019.100464. eCollection 2019 Jun. Mol Genet Metab Rep. 2019. PMID: 30891420 Free PMC article.
Sirtuins as regulators of the yeast metabolic network.
Ralser M, Michel S, Breitenbach M. Ralser M, et al. Among authors: michel s. Front Pharmacol. 2012 Mar 8;3:32. doi: 10.3389/fphar.2012.00032. eCollection 2012. Front Pharmacol. 2012. PMID: 22408620 Free PMC article.
A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging.
Timmermann B, Jarolim S, Russmayer H, Kerick M, Michel S, Krüger A, Bluemlein K, Laun P, Grillari J, Lehrach H, Breitenbach M, Ralser M. Timmermann B, et al. Among authors: michel s. Aging (Albany NY). 2010 Aug;2(8):475-86. doi: 10.18632/aging.100187. Aging (Albany NY). 2010. PMID: 20729566 Free PMC article.
The metabolic background is a global player in Saccharomyces gene expression epistasis.
Alam MT, Zelezniak A, Mülleder M, Shliaha P, Schwarz R, Capuano F, Vowinckel J, Radmanesfahar E, Krüger A, Calvani E, Michel S, Börno S, Christen S, Patil KR, Timmermann B, Lilley KS, Ralser M. Alam MT, et al. Among authors: michel s. Nat Microbiol. 2016 Feb 1;1:15030. doi: 10.1038/nmicrobiol.2015.30. Nat Microbiol. 2016. PMID: 27572163 Free PMC article.
Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.
Segal J, Mülleder M, Krüger A, Adler T, Scholze-Wittler M, Becker L, Calzada-Wack J, Garrett L, Hölter SM, Rathkolb B, Rozman J, Racz I, Fischer R, Busch DH, Neff F, Klingenspor M, Klopstock T, Grüning NM, Michel S, Lukaszewska-McGreal B, Voigt I, Hartmann L, Timmermann B, Lehrach H, Wolf E, Wurst W, Gailus-Durner V, Fuchs H, H de Angelis M, Schrewe H, Yuneva M, Ralser M. Segal J, et al. Among authors: michel s. J Inherit Metab Dis. 2019 Sep;42(5):839-849. doi: 10.1002/jimd.12105. Epub 2019 Jun 11. J Inherit Metab Dis. 2019. PMID: 31111503 Free PMC article.
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