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Protein kinase C-delta (PKCδ), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and survival in mice.
Parihar SP, Ozturk M, Marakalala MJ, Loots DT, Hurdayal R, Maasdorp DB, Van Reenen M, Zak DE, Darboe F, Penn-Nicholson A, Hanekom WA, Leitges M, Scriba TJ, Guler R, Brombacher F. Parihar SP, et al. Among authors: guler r. Mucosal Immunol. 2018 Mar;11(2):496-511. doi: 10.1038/mi.2017.68. Epub 2017 Aug 9. Mucosal Immunol. 2018. PMID: 28832027 Free article.
Host-directed drug therapy for tuberculosis.
Guler R, Brombacher F. Guler R, et al. Nat Chem Biol. 2015 Oct;11(10):748-51. doi: 10.1038/nchembio.1917. Nat Chem Biol. 2015. PMID: 26379013 No abstract available.
Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages.
Roy S, Schmeier S, Kaczkowski B, Arner E, Alam T, Ozturk M, Tamgue O, Parihar SP, Kawaji H, Itoh M, Lassmann T, Carninci P, Hayashizaki Y, Forrest ARR, Guler R, Bajic VB, Brombacher F, Suzuki H. Roy S, et al. Among authors: guler r. Sci Rep. 2018 Apr 30;8(1):6758. doi: 10.1038/s41598-018-24509-6. Sci Rep. 2018. PMID: 29712924 Free PMC article.
Batf2 differentially regulates tissue immunopathology in Type 1 and Type 2 diseases.
Guler R, Mpotje T, Ozturk M, Nono JK, Parihar SP, Chia JE, Abdel Aziz N, Hlaka L, Kumar S, Roy S, Penn-Nicholson A, Hanekom WA, Zak DE, Scriba TJ, Suzuki H, Brombacher F. Guler R, et al. Mucosal Immunol. 2019 Mar;12(2):390-402. doi: 10.1038/s41385-018-0108-2. Epub 2018 Dec 12. Mucosal Immunol. 2019. PMID: 30542107 Free PMC article.
Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages.
Tamgue O, Gcanga L, Ozturk M, Whitehead L, Pillay S, Jacobs R, Roy S, Schmeier S, Davids M, Medvedeva YA, Dheda K, Suzuki H, Brombacher F, Guler R. Tamgue O, et al. Among authors: guler r. Front Immunol. 2019 Mar 19;10:421. doi: 10.3389/fimmu.2019.00421. eCollection 2019. Front Immunol. 2019. PMID: 30941122 Free PMC article.
IL-4i1 Regulation of Immune Protection During Mycobacterium tuberculosis Infection.
Hlaka L, Ozturk M, Chia JE, Jones SS, Pillay S, Poswayo SKL, Mpotje T, Nono JK, Simelane SRN, Parihar SP, Roy S, Suzuki H, Brombacher F, Guler R. Hlaka L, et al. Among authors: guler r. J Infect Dis. 2021 Dec 15;224(12):2170-2180. doi: 10.1093/infdis/jiab558. J Infect Dis. 2021. PMID: 34739044 Free PMC article.
Evaluation of Berberine as an Adjunct to TB Treatment.
Ozturk M, Chia JE, Hazra R, Saqib M, Maine RA, Guler R, Suzuki H, Mishra BB, Brombacher F, Parihar SP. Ozturk M, et al. Among authors: guler r. Front Immunol. 2021 Oct 20;12:656419. doi: 10.3389/fimmu.2021.656419. eCollection 2021. Front Immunol. 2021. PMID: 34745081 Free PMC article.
99 results