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Page 1
Beamline K11 DIAD: a new instrument for dual imaging and diffraction at Diamond Light Source.
Reinhard C, Drakopoulos M, Ahmed SI, Deyhle H, James A, Charlesworth CM, Burt M, Sutter J, Alexander S, Garland P, Yates T, Marshall R, Kemp B, Warrick E, Pueyos A, Bradnick B, Nagni M, Winter AD, Filik J, Basham M, Wadeson N, King ONF, Aslani N, Dent AJ. Reinhard C, et al. Among authors: king onf. J Synchrotron Radiat. 2021 Nov 1;28(Pt 6):1985-1995. doi: 10.1107/S1600577521009875. Epub 2021 Oct 22. J Synchrotron Radiat. 2021. PMID: 34738954 Free PMC article.
A massively multi-scale approach to characterizing tissue architecture by synchrotron micro-CT applied to the human placenta.
Tun WM, Poologasundarampillai G, Bischof H, Nye G, King ONF, Basham M, Tokudome Y, Lewis RM, Johnstone ED, Brownbill P, Darrow M, Chernyavsky IL. Tun WM, et al. Among authors: king onf. J R Soc Interface. 2021 Jun;18(179):20210140. doi: 10.1098/rsif.2021.0140. Epub 2021 Jun 2. J R Soc Interface. 2021. PMID: 34062108 Free PMC article.
Non-competitive cyclic peptides for targeting enzyme-substrate complexes.
McAllister TE, Yeh TL, Abboud MI, Leung IKH, Hookway ES, King ONF, Bhushan B, Williams ST, Hopkinson RJ, Münzel M, Loik ND, Chowdhury R, Oppermann U, Claridge TDW, Goto Y, Suga H, Schofield CJ, Kawamura A. McAllister TE, et al. Among authors: king onf. Chem Sci. 2018 Apr 23;9(20):4569-4578. doi: 10.1039/c8sc00286j. eCollection 2018 May 28. Chem Sci. 2018. PMID: 29899950 Free PMC article.
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.
Kawamura A, Münzel M, Kojima T, Yapp C, Bhushan B, Goto Y, Tumber A, Katoh T, King ON, Passioura T, Walport LJ, Hatch SB, Madden S, Müller S, Brennan PE, Chowdhury R, Hopkinson RJ, Suga H, Schofield CJ. Kawamura A, et al. Nat Commun. 2017 Apr 6;8:14773. doi: 10.1038/ncomms14773. Nat Commun. 2017. PMID: 28382930 Free PMC article.
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.
Rotili D, Tomassi S, Conte M, Benedetti R, Tortorici M, Ciossani G, Valente S, Marrocco B, Labella D, Novellino E, Mattevi A, Altucci L, Tumber A, Yapp C, King ON, Hopkinson RJ, Kawamura A, Schofield CJ, Mai A. Rotili D, et al. J Med Chem. 2014 Jan 9;57(1):42-55. doi: 10.1021/jm4012802. Epub 2013 Dec 19. J Med Chem. 2014. PMID: 24325601
5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.
Hopkinson RJ, Tumber A, Yapp C, Chowdhury R, Aik W, Che KH, Li XS, Kristensen JBL, King ONF, Chan MC, Yeoh KK, Choi H, Walport LJ, Thinnes CC, Bush JT, Lejeune C, Rydzik AM, Rose NR, Bagg EA, McDonough MA, Krojer T, Yue WW, Ng SS, Olsen L, Brennan PE, Oppermann U, Muller-Knapp S, Klose RJ, Ratcliffe PJ, Schofield CJ, Kawamura A. Hopkinson RJ, et al. Among authors: king onf. Chem Sci. 2013 Aug 1;4(8):3110-3117. doi: 10.1039/C3SC51122G. Chem Sci. 2013. PMID: 26682036 Free PMC article.
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.
Rose NR, Woon EC, Tumber A, Walport LJ, Chowdhury R, Li XS, King ON, Lejeune C, Ng SS, Krojer T, Chan MC, Rydzik AM, Hopkinson RJ, Che KH, Daniel M, Strain-Damerell C, Gileadi C, Kochan G, Leung IK, Dunford J, Yeoh KK, Ratcliffe PJ, Burgess-Brown N, von Delft F, Muller S, Marsden B, Brennan PE, McDonough MA, Oppermann U, Klose RJ, Schofield CJ, Kawamura A. Rose NR, et al. J Med Chem. 2012 Jul 26;55(14):6639-43. doi: 10.1021/jm300677j. Epub 2012 Jul 11. J Med Chem. 2012. PMID: 22724510 Free PMC article.
Inhibition of histone demethylases by 4-carboxy-2,2'-bipyridyl compounds.
Chang KH, King ONF, Tumber A, Woon ECY, Heightman TD, McDonough MA, Schofield CJ, Rose NR. Chang KH, et al. Among authors: king onf. ChemMedChem. 2011 May 2;6(5):759-764. doi: 10.1002/cmdc.201100026. Epub 2011 Mar 15. ChemMedChem. 2011. PMID: 21412984 Free PMC article. No abstract available.
15 results