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A pharmacometric approach to define target site-specific breakpoints for bacterial killing and resistance suppression integrating microdialysis, time-kill curves and heteroresistance data: a case study with moxifloxacin.
Iqbal K, Broeker A, Nowak H, Rahmel T, Nussbaumer-Pröll A, Österreicher Z, Zeitlinger M, Wicha SG. Iqbal K, et al. Clin Microbiol Infect. 2020 Sep;26(9):1255.e1-1255.e8. doi: 10.1016/j.cmi.2020.02.013. Epub 2020 Feb 21. Clin Microbiol Infect. 2020. PMID: 32088331 Free article.
Single-dose pharmacokinetics of temocillin in plasma and soft tissues of healthy volunteers after intravenous and subcutaneous administration: a randomized crossover microdialysis trial.
Matzneller P, Ngougni Pokem P, Capron A, Lackner E, Wulkersdorfer B, Nussbaumer-Pröll A, Österreicher Z, Duchek M, Van de Velde S, Wallemacq PE, Mouton JW, Van Bambeke F, Zeitlinger M. Matzneller P, et al. J Antimicrob Chemother. 2020 Sep 1;75(9):2650-2656. doi: 10.1093/jac/dkaa176. J Antimicrob Chemother. 2020. PMID: 32433753 Clinical Trial.
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial.
Weiss A, Delavenne E, Matias C, Lagler H, Simon D, Li P, Hansen JU, Dos Santos TP, Jana B, Priemel P, Bangert C, Bauer M, Eberl S, Nussbaumer-Pröll A, Anne Österreicher Z, Matzneller P, Quint T, Weber M, Nielsen HM, Rades T, Johansen HK, Westh H, Kim W, Mylonakis E, Friis C, Guardabassi L, Pace J, Lundberg CV, M'Zali F, Butty P, Sørensen N, Nielsen HB, Toft-Kehler R, Guttman-Yassky E, Stingl G, Zeitlinger M, Sommer M. Weiss A, et al. Clin Transl Med. 2022 May;12(5):e790. doi: 10.1002/ctm2.790. Clin Transl Med. 2022. PMID: 35522900 Free PMC article. Clinical Trial.
20 results