Zisterer DM - Search Results

1

A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the JNK/STAT4/p66Shc axis.

Vanni F, Lopresti L, Zurli V, Kabanova A, Cattaneo F, Sicuranza A, Gozzetti A, Gemma S, Zisterer DM, Bocchia M, Campiani G, Baldari CT, Butini S, Ulivieri C. Vanni F, et al. Among authors: zisterer dm. Pharmacol Res. 2021 Dec;174:105965. doi: 10.1016/j.phrs.2021.105965. Epub 2021 Oct 31. Pharmacol Res. 2021. PMID: 34732370

2

Antiproliferative action of pyrrolobenzoxazepine derivatives in cultured cells: absence of correlation with binding to the peripheral-type benzodiazepine binding site.

Zisterer DM, Hance N, Campiani G, Garofalo A, Nacci V, Williams DC. Zisterer DM, et al. Biochem Pharmacol. 1998 Feb 15;55(4):397-403. doi: 10.1016/s0006-2952(97)00500-5. Biochem Pharmacol. 1998. PMID: 9514073

3

Pyrrolo-1,5-benzoxazepines induce apoptosis in HL-60, Jurkat, and Hut-78 cells: a new class of apoptotic agents.

Zisterer DM, Campiani G, Nacci V, Williams DC. Zisterer DM, et al. J Pharmacol Exp Ther. 2000 Apr;293(1):48-59. J Pharmacol Exp Ther. 2000. PMID: 10734152

4

Pyrrolo-1,5-benzoxazepines induce apoptosis in chronic myelogenous leukemia (CML) cells by bypassing the apoptotic suppressor bcr-abl.

Mc Gee MM, Campiani G, Ramunno A, Fattorusso C, Nacci V, Lawler M, Williams DC, Zisterer DM. Mc Gee MM, et al. Among authors: zisterer dm. J Pharmacol Exp Ther. 2001 Jan;296(1):31-40. J Pharmacol Exp Ther. 2001. PMID: 11123359

5

Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents.

Zisterer DM, McGee MM, Campiani G, Ramunno A, Fattorusso C, Nacci V, Lawler M, Williams DC. Zisterer DM, et al. Biochem Soc Trans. 2001 Nov;29(Pt 6):704-6. doi: 10.1042/0300-5127:0290704. Biochem Soc Trans. 2001. PMID: 11709059

6

Activation of the c-Jun N-terminal kinase (JNK) signaling pathway is essential during PBOX-6-induced apoptosis in chronic myelogenous leukemia (CML) cells.

Mc Gee MM, Campiani G, Ramunno A, Nacci V, Lawler M, Williams DC, Zisterer DM. Mc Gee MM, et al. Among authors: zisterer dm. J Biol Chem. 2002 May 24;277(21):18383-9. doi: 10.1074/jbc.M112058200. Epub 2002 Feb 20. J Biol Chem. 2002. PMID: 11856743 Free article.

7

Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6.

Mc Gee MM, Hyland E, Campiani G, Ramunno A, Nacci V, Zisterer DM. Mc Gee MM, et al. Among authors: zisterer dm. FEBS Lett. 2002 Mar 27;515(1-3):66-70. doi: 10.1016/s0014-5793(02)02440-7. FEBS Lett. 2002. PMID: 11943196 Free article.

8

Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR).

Campiani G, Ramunno A, Fiorini I, Nacci V, Morelli E, Novellino E, Goegan M, Mennini T, Sullivan S, Zisterer DM, Williams CD. Campiani G, et al. Among authors: zisterer dm. J Med Chem. 2002 Sep 12;45(19):4276-81. doi: 10.1021/jm020849l. J Med Chem. 2002. PMID: 12213069

9

Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human astrocytoma cells by the pyrrolo-1,5-benzoxazepine, PBOX-21.

Mulligan JM, Campiani G, Ramunno A, Nacci V, Zisterer DM. Mulligan JM, et al. Among authors: zisterer dm. Biochim Biophys Acta. 2003 Sep 1;1639(1):43-52. doi: 10.1016/s0925-4439(03)00128-5. Biochim Biophys Acta. 2003. PMID: 12943967 Free article.

10

Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactivation of Bcl-2 and Bcl-XL.

Mc Gee MM, Greene LM, Ledwidge S, Campiani G, Nacci V, Lawler M, Williams DC, Zisterer DM. Mc Gee MM, et al. Among authors: zisterer dm. J Pharmacol Exp Ther. 2004 Sep;310(3):1084-95. doi: 10.1124/jpet.104.067561. Epub 2004 May 13. J Pharmacol Exp Ther. 2004. PMID: 15143129

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