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Intracellular Staphylococcus aureus triggers pyroptosis and contributes to inhibition of healing due to perforin-2 suppression.
Pastar I, Sawaya AP, Marjanovic J, Burgess JL, Strbo N, Rivas KE, Wikramanayake TC, Head CR, Stone RC, Jozic I, Stojadinovic O, Kornfeld EY, Kirsner RS, Lev-Tov H, Tomic-Canic M. Pastar I, et al. Among authors: head cr. J Clin Invest. 2021 Dec 15;131(24):e133727. doi: 10.1172/JCI133727. J Clin Invest. 2021. PMID: 34730110 Free PMC article.
Single cell analyses reveal specific distribution of anti-bacterial molecule Perforin-2 in human skin and its modulation by wounding and Staphylococcus aureus infection.
Strbo N, Pastar I, Romero L, Chen V, Vujanac M, Sawaya AP, Jozic I, Ferreira ADF, Wong LL, Head C, Stojadinovic O, Garcia D, O'Neill K, Drakulich S, Taller S, Kirsner RS, Tomic-Canic M. Strbo N, et al. Exp Dermatol. 2019 Mar;28(3):225-232. doi: 10.1111/exd.13870. Epub 2019 Feb 12. Exp Dermatol. 2019. PMID: 30609079 Free PMC article.
Staphylococcus epidermidis Boosts Innate Immune Response by Activation of Gamma Delta T Cells and Induction of Perforin-2 in Human Skin.
Pastar I, O'Neill K, Padula L, Head CR, Burgess JL, Chen V, Garcia D, Stojadinovic O, Hower S, Plano GV, Thaller SR, Tomic-Canic M, Strbo N. Pastar I, et al. Among authors: head cr. Front Immunol. 2020 Sep 16;11:550946. doi: 10.3389/fimmu.2020.550946. eCollection 2020. Front Immunol. 2020. PMID: 33042139 Free PMC article.
Glucocorticoid-mediated induction of caveolin-1 disrupts cytoskeletal organization, inhibits cell migration and re-epithelialization of non-healing wounds.
Jozic I, Abujamra BA, Elliott MH, Wikramanayake TC, Marjanovic J, Stone RC, Head CR, Pastar I, Kirsner RS, Andreopoulos FM, Musi JP, Tomic-Canic M. Jozic I, et al. Among authors: head cr. Commun Biol. 2021 Jun 18;4(1):757. doi: 10.1038/s42003-021-02298-5. Commun Biol. 2021. PMID: 34145387 Free PMC article.
Catalase, a therapeutic target in the reversal of estrogen-mediated aging.
Elliot SJ, Catanuto P, Pereira-Simon S, Xia X, Pastar I, Thaller S, Head CR, Stojadinovic O, Tomic-Canic M, Glassberg MK. Elliot SJ, et al. Among authors: head cr. Mol Ther. 2022 Feb 2;30(2):947-962. doi: 10.1016/j.ymthe.2021.06.020. Epub 2021 Jun 24. Mol Ther. 2022. PMID: 34174444 Free PMC article.
Novel Cyclic Lipopeptides Fusaricidin Analogs for Treating Wound Infections.
Gil J, Pastar I, Houghten RA, Padhee S, Higa A, Solis M, Valdez J, Head CR, Michaels H, Lenhart B, Simms C, Williams B, Cudic P, Davis SC. Gil J, et al. Among authors: head cr. Front Microbiol. 2021 Jul 23;12:708904. doi: 10.3389/fmicb.2021.708904. eCollection 2021. Front Microbiol. 2021. PMID: 34367114 Free PMC article.
16 results