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Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane.
Zhao L, Chen F, Quitt O, Festag M, Ringelhan M, Wisskirchen K, Festag J, Yakovleva L, Sureau C, Bohne F, Aichler M, Bruss V, Shevtsov M, van de Klundert M, Momburg F, Möhl BS, Protzer U. Zhao L, et al. Among authors: ringelhan m. Cell Microbiol. 2021 Dec;23(12):e13399. doi: 10.1111/cmi.13399. Epub 2021 Nov 22. Cell Microbiol. 2021. PMID: 34729894
Canonical NF-κB signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response.
Sunami Y, Ringelhan M, Kokai E, Lu M, O'Connor T, Lorentzen A, Weber A, Rodewald AK, Müllhaupt B, Terracciano L, Gul S, Wissel S, Leithäuser F, Krappmann D, Riedl P, Hartmann D, Schirmbeck R, Strnad P, Hüser N, Kleeff J, Friess H, Schmid RM, Geisler F, Wirth T, Heikenwalder M. Sunami Y, et al. Among authors: ringelhan m. Hepatology. 2016 May;63(5):1592-607. doi: 10.1002/hep.28435. Epub 2016 Mar 4. Hepatology. 2016. PMID: 26892811 Free article.
Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication.
Hösel M, Quasdorff M, Ringelhan M, Kashkar H, Debey-Pascher S, Sprinzl MF, Bockmann JH, Arzberger S, Webb D, von Olshausen G, Weber A, Schultze JL, Büning H, Heikenwalder M, Protzer U. Hösel M, et al. Among authors: ringelhan m. Cell Mol Gastroenterol Hepatol. 2017 Jul 19;4(3):339-363. doi: 10.1016/j.jcmgh.2017.07.003. eCollection 2017 Nov. Cell Mol Gastroenterol Hepatol. 2017. PMID: 28884137 Free PMC article.
Viral hepatitis and liver cancer.
Ringelhan M, McKeating JA, Protzer U. Ringelhan M, et al. Philos Trans R Soc Lond B Biol Sci. 2017 Oct 19;372(1732):20160274. doi: 10.1098/rstb.2016.0274. Philos Trans R Soc Lond B Biol Sci. 2017. PMID: 28893941 Free PMC article. Review.
Correction to 'Viral hepatitis and liver cancer'.
Ringelhan M, McKeating JA, Protzer U. Ringelhan M, et al. Philos Trans R Soc Lond B Biol Sci. 2018 Jan 5;373(1737):20170339. doi: 10.1098/rstb.2017.0339. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29158320 Free PMC article. No abstract available.
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.
Burwitz BJ, Wettengel JM, Mück-Häusl MA, Ringelhan M, Ko C, Festag MM, Hammond KB, Northrup M, Bimber BN, Jacob T, Reed JS, Norris R, Park B, Moller-Tank S, Esser K, Greene JM, Wu HL, Abdulhaqq S, Webb G, Sutton WF, Klug A, Swanson T, Legasse AW, Vu TQ, Asokan A, Haigwood NL, Protzer U, Sacha JB. Burwitz BJ, et al. Among authors: ringelhan m. Nat Commun. 2017 Dec 15;8(1):2146. doi: 10.1038/s41467-017-01953-y. Nat Commun. 2017. PMID: 29247188 Free PMC article.
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