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Page 1
Cyclohexyl-griselimycin Is Active against Mycobacterium abscessus in Mice.
Aragaw WW, Roubert C, Fontaine E, Lagrange S, Zimmerman MD, Dartois V, Gengenbacher M, Dick T. Aragaw WW, et al. Among authors: fontaine e. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0140021. doi: 10.1128/AAC.01400-21. Epub 2021 Nov 1. Antimicrob Agents Chemother. 2022. PMID: 34723632 Free PMC article.
Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins.
Kling A, Lukat P, Almeida DV, Bauer A, Fontaine E, Sordello S, Zaburannyi N, Herrmann J, Wenzel SC, König C, Ammerman NC, Barrio MB, Borchers K, Bordon-Pallier F, Brönstrup M, Courtemanche G, Gerlitz M, Geslin M, Hammann P, Heinz DW, Hoffmann H, Klieber S, Kohlmann M, Kurz M, Lair C, Matter H, Nuermberger E, Tyagi S, Fraisse L, Grosset JH, Lagrange S, Müller R. Kling A, et al. Among authors: fontaine e. Science. 2015 Jun 5;348(6239):1106-12. doi: 10.1126/science.aaa4690. Science. 2015. PMID: 26045430
"Upcycling" known molecules and targets for drug-resistant TB.
Roubert C, Fontaine E, Upton AM. Roubert C, et al. Among authors: fontaine e. Front Cell Infect Microbiol. 2022 Oct 6;12:1029044. doi: 10.3389/fcimb.2022.1029044. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36275029 Free PMC article.
4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A): a potent and selective corticotrophin-releasing factor(1) receptor antagonist. I. Biochemical and pharmacological characterization.
Gully D, Geslin M, Serva L, Fontaine E, Roger P, Lair C, Darre V, Marcy C, Rouby PE, Simiand J, Guitard J, Gout G, Steinberg R, Rodier D, Griebel G, Soubrie P, Pascal M, Pruss R, Scatton B, Maffrand JP, Le Fur G. Gully D, et al. Among authors: fontaine e. J Pharmacol Exp Ther. 2002 Apr;301(1):322-32. doi: 10.1124/jpet.301.1.322. J Pharmacol Exp Ther. 2002. PMID: 11907190
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Hynds RE, Huebner A, Pearce DR, Hill MS, Akarca AU, Moore DA, Ward S, Gowers KHC, Karasaki T, Al Bakir M, Wilson GA, Pich O, Martínez-Ruiz C, Hossain ASMM, Pearce SP, Sivakumar M, Ben Aissa A, Grönroos E, Chandrasekharan D, Kolluri KK, Towns R, Wang K, Cook DE, Bosshard-Carter L, Naceur-Lombardelli C, Rowan AJ, Veeriah S, Litchfield K, Crosbie PAJ, Dive C, Quezada SA, Janes SM, Jamal-Hanjani M, Marafioti T; TRACERx consortium; McGranahan N, Swanton C. Hynds RE, et al. Nat Commun. 2024 May 31;15(1):4653. doi: 10.1038/s41467-024-47547-3. Nat Commun. 2024. PMID: 38821942 Free PMC article.
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity.
Al Assi A, Posty S, Lamarche F, Chebel A, Guitton J, Cottet-Rousselle C, Prudent R, Lafanechère L, Giraud S, Dallemagne P, Suzanne P, Verney A, Genestier L, Castets M, Fontaine E, Billaud M, Cordier-Bussat M. Al Assi A, et al. Among authors: fontaine e. Cell Death Dis. 2024 May 2;15(5):311. doi: 10.1038/s41419-024-06668-9. Cell Death Dis. 2024. PMID: 38697987 Free PMC article.
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
Pan X, AbdulJabbar K, Coelho-Lima J, Grapa AI, Zhang H, Cheung AHK, Baena J, Karasaki T, Wilson CR, Sereno M, Veeriah S, Aitken SJ, Hackshaw A, Nicholson AG, Jamal-Hanjani M; TRACERx Consortium; Swanton C, Yuan Y, Le Quesne J, Moore DA. Pan X, et al. Nat Cancer. 2024 Feb;5(2):347-363. doi: 10.1038/s43018-023-00694-w. Epub 2024 Jan 10. Nat Cancer. 2024. PMID: 38200244 Free PMC article.
333 results