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An automated platform for structural analysis of membrane proteins through serial crystallography.
Cell Rep Methods. 2021 Oct 25;1(6):None. doi: 10.1016/j.crmeth.2021.100102.
Cell Rep Methods. 2021.
PMID: 34723237
Free PMC article.
Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.
Vasiliauskaité-Brooks I, Healey RD, Rochaix P, Saint-Paul J, Sounier R, Grison C, Waltrich-Augusto T, Fortier M, Hoh F, Saied EM, Arenz C, Basu S, Leyrat C, Granier S.
Vasiliauskaité-Brooks I, et al. Among authors: healey rd.
Nat Commun. 2018 Dec 21;9(1):5437. doi: 10.1038/s41467-018-07864-w.
Nat Commun. 2018.
PMID: 30575723
Free PMC article.
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7TM proteins are not necessarily GPCRs.
Vasiliauskaité-Brooks I, Healey RD, Granier S.
Vasiliauskaité-Brooks I, et al. Among authors: healey rd.
Mol Cell Endocrinol. 2019 Jul 1;491:110397. doi: 10.1016/j.mce.2019.02.009. Epub 2019 Apr 24.
Mol Cell Endocrinol. 2019.
PMID: 31026477
Review.
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Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases.
Healey RD, Saied EM, Cong X, Karsai G, Gabellier L, Saint-Paul J, Del Nero E, Jeannot S, Drapeau M, Fontanel S, Maurel D, Basu S, Leyrat C, Golebiowski J, Bossis G, Bechara C, Hornemann T, Arenz C, Granier S.
Healey RD, et al.
Angew Chem Int Ed Engl. 2022 Jan 10;61(2):e202109967. doi: 10.1002/anie.202109967. Epub 2021 Nov 25.
Angew Chem Int Ed Engl. 2022.
PMID: 34668624
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Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies.
Healey RD, Couillaud L, Hoh F, Mouhand A, Fouillen A, Couvineau P, Granier S, Leyrat C.
Healey RD, et al.
Commun Chem. 2023 Jul 28;6(1):160. doi: 10.1038/s42004-023-00962-x.
Commun Chem. 2023.
PMID: 37507458
Free PMC article.
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Design, Synthesis, and Evaluation of N- and C-Terminal Protein Bioconjugates as G Protein-Coupled Receptor Agonists.
Healey RD, Wojciechowski JP, Monserrat-Martinez A, Tan SL, Marquis CP, Sierecki E, Gambin Y, Finch AM, Thordarson P.
Healey RD, et al.
Bioconjug Chem. 2018 Feb 21;29(2):403-409. doi: 10.1021/acs.bioconjchem.7b00716. Epub 2018 Feb 2.
Bioconjug Chem. 2018.
PMID: 29328675
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An improved process for the production of highly purified recombinant thaumatin tagged-variants.
Healey RD, Lebhar H, Hornung S, Thordarson P, Marquis CP.
Healey RD, et al.
Food Chem. 2017 Dec 15;237:825-832. doi: 10.1016/j.foodchem.2017.06.018. Epub 2017 Jun 13.
Food Chem. 2017.
PMID: 28764073
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A bacterial chloroform reductive dehalogenase: purification and biochemical characterization.
Jugder BE, Bohl S, Lebhar H, Healey RD, Manefield M, Marquis CP, Lee M.
Jugder BE, et al. Among authors: healey rd.
Microb Biotechnol. 2017 Nov;10(6):1640-1648. doi: 10.1111/1751-7915.12745. Epub 2017 Jun 20.
Microb Biotechnol. 2017.
PMID: 28631300
Free PMC article.
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