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Dual role of allele-specific DNA hypermethylation within the TERT promoter in cancer.
Lee DD, Komosa M, Sudhaman S, Leão R, Zhang CH, Apolonio JD, Hermanns T, Wild PJ, Klocker H, Nassiri F, Zadeh G, Diplas BH, Yan H, Gallinger S, Pugh TJ, Ramaswamy V, Taylor MD, Castelo-Branco P, Nunes NM, Tabori U. Lee DD, et al. Among authors: wild pj. J Clin Invest. 2021 Nov 1;131(21):e146915. doi: 10.1172/JCI146915. J Clin Invest. 2021. PMID: 34720085 Free PMC article.
DNA hypermethylation within TERT promoter upregulates TERT expression in cancer.
Lee DD, Leão R, Komosa M, Gallo M, Zhang CH, Lipman T, Remke M, Heidari A, Nunes NM, Apolónio JD, Price AJ, De Mello RA, Dias JS, Huntsman D, Hermanns T, Wild PJ, Vanner R, Zadeh G, Karamchandani J, Das S, Taylor MD, Hawkins CE, Wasserman JD, Figueiredo A, Hamilton RJ, Minden MD, Wani K, Diplas B, Yan H, Aldape K, Akbari MR, Danesh A, Pugh TJ, Dirks PB, Castelo-Branco P, Tabori U. Lee DD, et al. Among authors: wild pj. J Clin Invest. 2019 Jan 2;129(1):223-229. doi: 10.1172/JCI121303. Epub 2018 Dec 3. J Clin Invest. 2019. PMID: 30358567 Free PMC article.
Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behavior of bladder cancer.
Leão R, Lee D, Figueiredo A, Hermanns T, Wild P, Komosa M, Lau I, Mistry M, Nunes NM, Price AJ, Zhang C, Lipman T, Poyet C, Valtcheva N, Oehl K, Coelho H, Sayyid R, Gomes AM, Prado E Castro L, Sweet J, Vinagre J, Apolónio J, Stephens D, Faleiro I, Fadaak K, Richard PO, Kulkarni G, Zlotta AR, Hamilton RJ, Castelo-Branco P, Tabori U. Leão R, et al. Int J Cancer. 2019 Apr 1;144(7):1676-1684. doi: 10.1002/ijc.31935. Epub 2018 Dec 30. Int J Cancer. 2019. PMID: 30350309 Free PMC article.
DNA hypermethylation within TERT promoter upregulates TERT expression in cancer.
Lee DD, Leão R, Komosa M, Gallo M, Zhang CH, Lipman T, Remke M, Heidari A, Nunes NM, Apolónio JD, Price AJ, De Mello RA, Dias JS, Huntsman D, Hermanns T, Wild PJ, Vanner R, Zadeh G, Karamchandani J, Das S, Taylor MD, Hawkins CE, Wasserman JD, Figueiredo A, Hamilton RJ, Minden MD, Wani K, Diplas B, Yan H, Aldape K, Akbari MR, Danesh A, Pugh TJ, Dirks PB, Castelo-Branco P, Tabori U. Lee DD, et al. Among authors: wild pj. J Clin Invest. 2019 Apr 1;129(4):1801. doi: 10.1172/JCI128527. Epub 2019 Apr 1. J Clin Invest. 2019. PMID: 30932912 Free PMC article. No abstract available.
Aberrant methylated key genes of methyl group metabolism within the molecular etiology of urothelial carcinogenesis.
Erichsen L, Ghanjati F, Beermann A, Poyet C, Hermanns T, Schulz WA, Seifert HH, Wild PJ, Buser L, Kröning A, Braunstein S, Anlauf M, Jankowiak S, Hassan M, Bendhack ML, Araúzo-Bravo MJ, Santourlidis S. Erichsen L, et al. Among authors: wild pj. Sci Rep. 2018 Feb 22;8(1):3477. doi: 10.1038/s41598-018-21932-7. Sci Rep. 2018. PMID: 29472622 Free PMC article.
The androgen-regulated Calcium-Activated Nucleotidase 1 (CANT1) is commonly overexpressed in prostate cancer and is tumor-biologically relevant in vitro.
Gerhardt J, Steinbrech C, Büchi O, Behnke S, Bohnert A, Fritzsche F, Liewen H, Stenner F, Wild P, Hermanns T, Müntener M, Dietel M, Jung K, Stephan C, Kristiansen G. Gerhardt J, et al. Am J Pathol. 2011 Apr;178(4):1847-60. doi: 10.1016/j.ajpath.2010.12.046. Am J Pathol. 2011. PMID: 21435463 Free PMC article.
A noninvasive urine-based methylation biomarker panel to detect bladder cancer and discriminate cancer grade.
Hermanns T, Savio AJ, Olkhov-Mitsel E, Mari A, Wettstein MS, Saba K, Bhindi B, Kuk C, Poyet C, Wild PJ, Noon A, Bashir S, Juvet T, Rendon RA, Waltregny D, van der Kwast T, Finelli A, Kulkarni GS, Fleshner NE, Lo K, Bapat B, Zlotta AR. Hermanns T, et al. Among authors: wild pj. Urol Oncol. 2020 Jun;38(6):603.e1-603.e7. doi: 10.1016/j.urolonc.2020.01.007. Epub 2020 Feb 18. Urol Oncol. 2020. PMID: 32081560
316 results