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Physiologically based pharmacokinetic modeling to predict the impact of liver cirrhosis on glucuronidation via UGT1A4 & UGT2B7/2B4 - a case study with midazolam.
Ozbey AC, Keemink J, Wagner B, Pugliano A, Krähenbühl S, Annaert P, Fowler S, Parrott N, Umehara K. Ozbey AC, et al. Among authors: umehara k. Drug Metab Dispos. 2024 Apr 23:DMD-AR-2023-001635. doi: 10.1124/dmd.123.001635. Online ahead of print. Drug Metab Dispos. 2024. PMID: 38653501 Free article.
Investigating Tacrolimus Disposition in Paediatric Patients with a Physiologically Based Pharmacokinetic Model Incorporating CYP3A4 Ontogeny, Mechanistic Absorption and Red Blood Cell Binding.
Van der Veken M, Brouwers J, Ozbey AC, Umehara K, Stillhart C, Knops N, Augustijns P, Parrott NJ. Van der Veken M, et al. Among authors: umehara k. Pharmaceutics. 2023 Aug 29;15(9):2231. doi: 10.3390/pharmaceutics15092231. Pharmaceutics. 2023. PMID: 37765200 Free PMC article.
A JROD survey: nationwide overview of radiotherapy data from 2015 to 2021.
Ohba H, Nakada Y, Numasaki H, Umehara K, Ota J, Okuda Y, Teshima T, Ogawa K, Nakamura K, Japanese Society For Radiation Oncology Database Committee. Ohba H, et al. Among authors: umehara k. J Radiat Res. 2023 Nov 21;64(6):904-910. doi: 10.1093/jrr/rrad067. J Radiat Res. 2023. PMID: 37738418 Free PMC article.
270 results