Husbands SM - Search Results

1

Long-term antagonism and allosteric regulation of mu opioid receptors by the novel ligand, methocinnamox.

Zamora JC, Smith HR, Jennings EM, Chavera TS, Kotipalli V, Jay A, Husbands SM, Disney A, Berg KA, Clarke WP. Zamora JC, et al. Among authors: husbands sm. Pharmacol Res Perspect. 2021 Dec;9(6):e00887. doi: 10.1002/prp2.887. Pharmacol Res Perspect. 2021. PMID: 34713624 Free PMC article.

2

Opioid ligands having delayed long-term antagonist activity: potential pharmacotherapies for opioid abuse.

Husbands SM, Lewis JW. Husbands SM, et al. Mini Rev Med Chem. 2003 Mar;3(2):137-44. doi: 10.2174/1389557033405395. Mini Rev Med Chem. 2003. PMID: 12570846 Review.

3

BU74, a complex oripavine derivative with potent kappa opioid receptor agonism and delayed opioid antagonism.

Husbands SM, Neilan CL, Broadbear J, Grundt P, Breeden S, Aceto MD, Woods JH, Lewis JW, Traynor JR. Husbands SM, et al. Eur J Pharmacol. 2005 Feb 21;509(2-3):117-25. doi: 10.1016/j.ejphar.2004.12.035. Eur J Pharmacol. 2005. PMID: 15733546

4

In vivo and in vitro characterization of naltrindole-derived ligands at the κ-opioid receptor.

Casal-Dominguez JJ, Clark M, Traynor JR, Husbands SM, Bailey SJ. Casal-Dominguez JJ, et al. Among authors: husbands sm. J Psychopharmacol. 2013 Feb;27(2):192-202. doi: 10.1177/0269881112464828. Epub 2012 Oct 31. J Psychopharmacol. 2013. PMID: 23118019 Free PMC article.

5

Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization.

Lowe JD, Sanderson HS, Cooke AE, Ostovar M, Tsisanova E, Withey SL, Chavkin C, Husbands SM, Kelly E, Henderson G, Bailey CP. Lowe JD, et al. Among authors: husbands sm. Mol Pharmacol. 2015 Aug;88(2):347-56. doi: 10.1124/mol.115.098293. Epub 2015 May 26. Mol Pharmacol. 2015. PMID: 26013542 Free PMC article.

6

The novel μ-opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception.

Hill R, Disney A, Conibear A, Sutcliffe K, Dewey W, Husbands S, Bailey C, Kelly E, Henderson G. Hill R, et al. Br J Pharmacol. 2018 Jul;175(13):2653-2661. doi: 10.1111/bph.14224. Epub 2018 May 14. Br J Pharmacol. 2018. PMID: 29582414 Free PMC article.

7

Long-Lasting Effects of Methocinnamox on Opioid Self-Administration in Rhesus Monkeys.

Maguire DR, Gerak LR, Woods JH, Husbands SM, Disney A, France CP. Maguire DR, et al. Among authors: husbands sm. J Pharmacol Exp Ther. 2019 Jan;368(1):88-99. doi: 10.1124/jpet.118.252353. Epub 2018 Nov 6. J Pharmacol Exp Ther. 2019. PMID: 30401680 Free PMC article.

8

Reversal and Prevention of the Respiratory-Depressant Effects of Heroin by the Novel μ-Opioid Receptor Antagonist Methocinnamox in Rhesus Monkeys.

Gerak LR, Maguire DR, Woods JH, Husbands SM, Disney A, France CP. Gerak LR, et al. Among authors: husbands sm. J Pharmacol Exp Ther. 2019 Feb;368(2):229-236. doi: 10.1124/jpet.118.253286. Epub 2018 Nov 21. J Pharmacol Exp Ther. 2019. PMID: 30463875 Free PMC article.

9

Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats.

Gerak LR, Minervini V, Latham E, Ghodrati S, Lillis KV, Wooden J, Disney A, Husbands SM, France CP. Gerak LR, et al. Among authors: husbands sm. J Pharmacol Exp Ther. 2019 Nov;371(2):507-516. doi: 10.1124/jpet.119.260331. Epub 2019 Aug 22. J Pharmacol Exp Ther. 2019. PMID: 31439807 Free PMC article.

10

OREX-1019: A Novel Treatment of Opioid Use Disorder and Relapse Prevention.

Maguire DR, Gerak LR, Cami-Kobeci G, Husbands SM, France CP, Belli B, Flynn P. Maguire DR, et al. Among authors: husbands sm. J Pharmacol Exp Ther. 2020 Feb;372(2):205-215. doi: 10.1124/jpet.119.261511. Epub 2019 Nov 20. J Pharmacol Exp Ther. 2020. PMID: 31748404 Free PMC article.

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