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Heterogeneity of Circulating Tumor Cell-Associated Genomic Gains in Breast Cancer and Its Association with the Host Immune Response.
Kanwar N, Balde Z, Nair R, Dawe M, Chen S, Maganti M, Atenafu EG, Manolescu S, Wei C, Mao A, Fu F, Wang D, Cheung A, Yerofeyeva Y, Peters R, Liu K, Desmedt C, Sotiriou C, Szekely B, Kulka J, McKee TD, Hirano N, Bartlett JMS, Yaffe MJ, Bedard PL, McCready D, Done SJ. Kanwar N, et al. Among authors: mao a. Cancer Res. 2021 Dec 15;81(24):6196-6206. doi: 10.1158/0008-5472.CAN-21-1079. Epub 2021 Oct 28. Cancer Res. 2021. PMID: 34711609 Free PMC article.
Identification and optimization of nitrophenolic analogues as dopamine metabolic enzyme inhibitors for the treatment of Parkinson's disease.
Zou M, Wu Y, Lan Y, Xie H, Sun H, Liu W, Feng F, Jiang X. Zou M, et al. Bioorg Chem. 2024 May 23;148:107488. doi: 10.1016/j.bioorg.2024.107488. Online ahead of print. Bioorg Chem. 2024. PMID: 38797066
Simultaneous inhibition of the two key dopamine metabolic enzymes, catechol-O-methyltransferase (COMT) and monoamine oxidase B (MAO-B), could potentially be a breakthrough in achieving clinical efficacy. ...
Simultaneous inhibition of the two key dopamine metabolic enzymes, catechol-O-methyltransferase (COMT) and monoamine oxidase B …
Development of scoring-assisted generative exploration (SAGE) and its application to dual inhibitor design for acetylcholinesterase and monoamine oxidase B.
Lim H. Lim H. J Cheminform. 2024 May 24;16(1):59. doi: 10.1186/s13321-024-00845-w. J Cheminform. 2024. PMID: 38790018 Free PMC article.
Furthermore, I suggested a top-ranked molecule with SAGE as dual inhibitors of acetylcholinesterase and monoamine oxidase B through multiple desired property optimization. ...Additionally, the application of SAGE to discover dual inhibitors for acetylcholinesterase …
Furthermore, I suggested a top-ranked molecule with SAGE as dual inhibitors of acetylcholinesterase and monoamine oxidase B th …
Role of Vasoactive Hormone-Induced Signal Transduction in Cardiac Hypertrophy and Heart Failure.
Dhalla NS, Mota KO, Elimban V, Shah AK, de Vasconcelos CML, Bhullar SK. Dhalla NS, et al. Cells. 2024 May 17;13(10):856. doi: 10.3390/cells13100856. Cells. 2024. PMID: 38786079 Free PMC article. Review.
The prolonged exposure of the hypertrophied heart to these vasoactive hormones has been reported to result in the oxidation of catecholamines and serotonin via monoamine oxidase as well as the activation of NADPH oxidase via angiotensin II and endothelins to …
The prolonged exposure of the hypertrophied heart to these vasoactive hormones has been reported to result in the oxidation of catecholamine …
Construction of Multi-enzyme Integrated Catalysts for Deracemization of Cyclic Chiral Amines.
Zhou L, Li C, Dong L, Liu Y, He Y, Liu G, Bai J, Ma L, Jiang Y. Zhou L, et al. Chembiochem. 2024 May 22:e202400346. doi: 10.1002/cbic.202400346. Online ahead of print. Chembiochem. 2024. PMID: 38775416
In this research, we designed a four-enzyme integrated catalyst and used it to catalyse the racemization reaction of cyclic chiral amines, where monoamine oxidase (MAO) catalyses the selective oxidation of 1-methyl-1,2,3,4-tetrahydroisoquinoline (MTQ), imine reducta …
In this research, we designed a four-enzyme integrated catalyst and used it to catalyse the racemization reaction of cyclic chiral amines, w …
5,7-dihydroxy-3',4',5'-trimethoxyflavone mitigates lead induced neurotoxicity in rats via its chelating, antioxidant, anti-inflammatory and monoaminergic properties.
Singh V, Shri R, Sood P, Singh M, Singh TG, Singh R, Kumar A, Ahmad SF. Singh V, et al. Food Chem Toxicol. 2024 May 18;189:114747. doi: 10.1016/j.fct.2024.114747. Online ahead of print. Food Chem Toxicol. 2024. PMID: 38768937
Cognitive and motor functions were assessed using Morris Water Maze and horizontal bar tests. Lead, monoamine oxidase (MAO) A and B enzymes, reduced glutathione (GSH), thiobarbituric acid reactive species (TBARS), Tumor necrosis factor-alpha (TNF-alpha …
Cognitive and motor functions were assessed using Morris Water Maze and horizontal bar tests. Lead, monoamine oxidase (MAO …
26,210 results
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