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THN 102 for Excessive Daytime Sleepiness Associated with Parkinson's Disease: A Phase 2a Trial.
Corvol JC, Azulay JP, Bosse B, Dauvilliers Y, Defebvre L, Klostermann F, Kovacs N, Maltête D, Ondo WG, Pahwa R, Rein W, Thobois S, Valis M, Videnovic A, Rascol O; THN102-202 Study Investigators. Corvol JC, et al. Among authors: rein w. Mov Disord. 2022 Feb;37(2):410-415. doi: 10.1002/mds.28840. Epub 2021 Oct 28. Mov Disord. 2022. PMID: 34709684 Clinical Trial.
Efficacy of THN102 (a combination of modafinil and flecainide) on vigilance and cognition during 40-hour total sleep deprivation in healthy subjects: Glial connexins as a therapeutic target.
Sauvet F, Erblang M, Gomez-Merino D, Rabat A, Guillard M, Dubourdieu D, Lefloch H, Drogou C, Van Beers P, Bougard C, Bourrrilhon C, Arnal P, Rein W, Mouthon F, Brunner-Ferber F, Leger D, Dauvilliers Y, Chennaoui M, Charvériat M. Sauvet F, et al. Among authors: rein w. Br J Clin Pharmacol. 2019 Nov;85(11):2623-2633. doi: 10.1111/bcp.14098. Epub 2019 Sep 15. Br J Clin Pharmacol. 2019. PMID: 31419329 Free PMC article. Clinical Trial.
Connexins as therapeutic targets in neurological and neuropsychiatric disorders.
Charvériat M, Mouthon F, Rein W, Verkhratsky A. Charvériat M, et al. Among authors: rein w. Biochim Biophys Acta Mol Basis Dis. 2021 May 1;1867(5):166098. doi: 10.1016/j.bbadis.2021.166098. Epub 2021 Feb 3. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33545299 Free article. Review.
35 results