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Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function.
Hawley KM, Eclov RJ, Schnorenberg MR, Tian Y, Shah RN, Thomas-Toth AT, Fefferman M, Bird GH, Walensky LD, Tirrell MV, LaBelle JL. Hawley KM, et al. Among authors: labelle jl. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2209044119. doi: 10.1073/pnas.2209044119. Epub 2022 Oct 13. Proc Natl Acad Sci U S A. 2022. PMID: 36227917 Free PMC article.
Dual Targeting of Apoptotic and Signaling Pathways in T-Lineage Acute Lymphoblastic Leukemia.
Saygin C, Giordano G, Shimamoto K, Eisfelder B, Thomas-Toth A, Venkataraman G, Ananthanarayanan V, Vincent TL, DuVall A, Patel AA, Chen Y, Tan F, Anthony SP, Chen Y, Shen Y, Odenike O, Teachey DT, Kee BL, LaBelle J, Stock W. Saygin C, et al. Clin Cancer Res. 2023 Aug 15;29(16):3151-3161. doi: 10.1158/1078-0432.CCR-23-0415. Clin Cancer Res. 2023. PMID: 37363966 Free PMC article.
Targeted Polymersome Delivery of a Stapled Peptide for Drugging the Tumor Protein p53:BCL-2-Family Axis in Diffuse Large B-Cell Lymphoma.
Schnorenberg MR, Hawley KM, Thomas-Toth AT, Watkins EA, Tian Y, Ting JM, Leak LB, Kucera IM, Raczy MM, Kung AL, Hubbell JA, Tirrell MV, LaBelle JL. Schnorenberg MR, et al. Among authors: labelle jl. ACS Nano. 2023 Dec 12;17(23):23374-23390. doi: 10.1021/acsnano.3c04112. Epub 2023 Sep 9. ACS Nano. 2023. PMID: 37688780 Free PMC article.
Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide.
Hadji A, Schmitt GK, Schnorenberg MR, Roach L, Hickey CM, Leak LB, Tirrell MV, LaBelle JL. Hadji A, et al. Among authors: labelle jl. Oncotarget. 2019 Oct 22;10(58):6219-6233. doi: 10.18632/oncotarget.27262. eCollection 2019 Oct 22. Oncotarget. 2019. PMID: 31692812 Free PMC article.
57 results