Sabatini DM - Search Results

1

GCN2 adapts protein synthesis to scavenging-dependent growth.

Nofal M, Wang T, Yang L, Jankowski CSR, Hsin-Jung Li S, Han S, Parsons L, Frese AN, Gitai Z, Anthony TG, Wühr M, Sabatini DM, Rabinowitz JD. Nofal M, et al. Among authors: sabatini dm. Cell Syst. 2022 Feb 16;13(2):158-172.e9. doi: 10.1016/j.cels.2021.09.014. Epub 2021 Oct 26. Cell Syst. 2022. PMID: 34706266 Free PMC article.

2

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.

Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Among authors: sabatini dm. Cell. 2002 Jul 26;110(2):163-75. doi: 10.1016/s0092-8674(02)00808-5. Cell. 2002. PMID: 12150925 Free article.

3

eIF3: a connecTOR of S6K1 to the translation preinitiation complex.

Peterson TR, Sabatini DM. Peterson TR, et al. Among authors: sabatini dm. Mol Cell. 2005 Dec 9;20(5):655-7. doi: 10.1016/j.molcel.2005.11.016. Mol Cell. 2005. PMID: 16337588 Free article. Review.

4

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.

Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM. Peterson TR, et al. Among authors: sabatini dm. Cell. 2009 May 29;137(5):873-86. doi: 10.1016/j.cell.2009.03.046. Epub 2009 May 14. Cell. 2009. PMID: 19446321 Free PMC article.

5

mTOR signaling at a glance.

Laplante M, Sabatini DM. Laplante M, et al. Among authors: sabatini dm. J Cell Sci. 2009 Oct 15;122(Pt 20):3589-94. doi: 10.1242/jcs.051011. J Cell Sci. 2009. PMID: 19812304 Free PMC article. Review. No abstract available.

6

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.

Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM. Sancak Y, et al. Among authors: sabatini dm. Cell. 2010 Apr 16;141(2):290-303. doi: 10.1016/j.cell.2010.02.024. Epub 2010 Apr 8. Cell. 2010. PMID: 20381137 Free PMC article.

7

Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo.

Sheen JH, Zoncu R, Kim D, Sabatini DM. Sheen JH, et al. Among authors: sabatini dm. Cancer Cell. 2011 May 17;19(5):613-28. doi: 10.1016/j.ccr.2011.03.012. Cancer Cell. 2011. PMID: 21575862 Free PMC article.

8

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, Sabatini DM. Peterson TR, et al. Among authors: sabatini dm. Cell. 2011 Aug 5;146(3):408-20. doi: 10.1016/j.cell.2011.06.034. Cell. 2011. PMID: 21816276 Free PMC article.

9

mTOR signaling in growth control and disease.

Laplante M, Sabatini DM. Laplante M, et al. Among authors: sabatini dm. Cell. 2012 Apr 13;149(2):274-93. doi: 10.1016/j.cell.2012.03.017. Cell. 2012. PMID: 22500797 Free PMC article. Review.

10

A unifying model for mTORC1-mediated regulation of mRNA translation.

Thoreen CC, Chantranupong L, Keys HR, Wang T, Gray NS, Sabatini DM. Thoreen CC, et al. Among authors: sabatini dm. Nature. 2012 May 2;485(7396):109-13. doi: 10.1038/nature11083. Nature. 2012. PMID: 22552098 Free PMC article.

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