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GCN2 adapts protein synthesis to scavenging-dependent growth.
Nofal M, Wang T, Yang L, Jankowski CSR, Hsin-Jung Li S, Han S, Parsons L, Frese AN, Gitai Z, Anthony TG, Wühr M, Sabatini DM, Rabinowitz JD. Nofal M, et al. Among authors: anthony tg. Cell Syst. 2022 Feb 16;13(2):158-172.e9. doi: 10.1016/j.cels.2021.09.014. Epub 2021 Oct 26. Cell Syst. 2022. PMID: 34706266 Free PMC article.
GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment.
Wilson GJ, Lennox BA, She P, Mirek ET, Al Baghdadi RJ, Fusakio ME, Dixon JL, Henderson GC, Wek RC, Anthony TG. Wilson GJ, et al. Among authors: anthony tg. Am J Physiol Endocrinol Metab. 2015 Feb 15;308(4):E283-93. doi: 10.1152/ajpendo.00361.2014. Epub 2014 Dec 9. Am J Physiol Endocrinol Metab. 2015. PMID: 25491724 Free PMC article.
Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids.
Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, Li X, Zhan L, White E, Anthony TG, Rabinowitz JD, Arany Z. Neinast MD, et al. Among authors: anthony tg. Cell Metab. 2019 Feb 5;29(2):417-429.e4. doi: 10.1016/j.cmet.2018.10.013. Epub 2018 Nov 15. Cell Metab. 2019. PMID: 30449684 Free PMC article.
Discordant regulation of eIF2 kinase GCN2 and mTORC1 during nutrient stress.
Misra J, Holmes MJ, T Mirek E, Langevin M, Kim HG, Carlson KR, Watford M, Dong XC, Anthony TG, Wek RC. Misra J, et al. Among authors: anthony tg. Nucleic Acids Res. 2021 Jun 4;49(10):5726-5742. doi: 10.1093/nar/gkab362. Nucleic Acids Res. 2021. PMID: 34023907 Free PMC article.
Circulating metabolite homeostasis achieved through mass action.
Li X, Hui S, Mirek ET, Jonsson WO, Anthony TG, Lee WD, Zeng X, Jang C, Rabinowitz JD. Li X, et al. Among authors: anthony tg. Nat Metab. 2022 Jan;4(1):141-152. doi: 10.1038/s42255-021-00517-1. Epub 2022 Jan 20. Nat Metab. 2022. PMID: 35058631 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35555171
GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis.
Cordova RA, Misra J, Amin PH, Klunk AJ, Damayanti NP, Carlson KR, Elmendorf AJ, Kim HG, Mirek ET, Elzey BD, Miller MJ, Dong XC, Cheng L, Anthony TG, Pili R, Wek RC, Staschke KA. Cordova RA, et al. Among authors: anthony tg. Elife. 2022 Sep 15;11:e81083. doi: 10.7554/eLife.81083. Elife. 2022. PMID: 36107759 Free PMC article.
89 results