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Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.
Schönberger K, Obier N, Romero-Mulero MC, Cauchy P, Mess J, Pavlovich PV, Zhang YW, Mitterer M, Rettkowski J, Lalioti ME, Jäcklein K, Curtis JD, Féret B, Sommerkamp P, Morganti C, Ito K, Ghyselinck NB, Trompouki E, Buescher JM, Pearce EL, Cabezas-Wallscheid N. Schönberger K, et al. Among authors: ghyselinck nb. Cell Stem Cell. 2022 Jan 6;29(1):131-148.e10. doi: 10.1016/j.stem.2021.10.002. Epub 2021 Oct 26. Cell Stem Cell. 2022. PMID: 34706256 Free PMC article.
Spermatogonia differentiation requires retinoic acid receptor γ.
Gely-Pernot A, Raverdeau M, Célébi C, Dennefeld C, Feret B, Klopfenstein M, Yoshida S, Ghyselinck NB, Mark M. Gely-Pernot A, et al. Among authors: ghyselinck nb. Endocrinology. 2012 Jan;153(1):438-49. doi: 10.1210/en.2011-1102. Epub 2011 Nov 1. Endocrinology. 2012. PMID: 22045663
Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.
Raverdeau M, Gely-Pernot A, Féret B, Dennefeld C, Benoit G, Davidson I, Chambon P, Mark M, Ghyselinck NB. Raverdeau M, et al. Among authors: ghyselinck nb. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16582-7. doi: 10.1073/pnas.1214936109. Epub 2012 Sep 24. Proc Natl Acad Sci U S A. 2012. PMID: 23012458 Free PMC article.
115 results